Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   U14A_RS18645 Genome accession   NZ_CP035516
Coordinates   3720593..3721225 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain U14A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3715593..3726225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U14A_RS18620 (U14A_03584) yheS 3715762..3717675 (+) 1914 WP_000634830.1 ABC transporter ATP-binding protein -
  U14A_RS18625 (U14A_03585) yheT 3717675..3718697 (+) 1023 WP_000057364.1 hydrolase -
  U14A_RS18630 (U14A_03586) yheU 3718691..3718909 (+) 219 WP_000907085.1 YheU family protein -
  U14A_RS18635 (U14A_03587) prkB 3718963..3719832 (+) 870 WP_001274684.1 phosphoribulokinase -
  U14A_RS18640 (U14A_03588) yhfA 3719887..3720291 (-) 405 WP_001148908.1 OsmC family protein -
  U14A_RS18645 (U14A_03589) crp 3720593..3721225 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  U14A_RS18650 (U14A_03590) yhfK 3721276..3723366 (+) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  U14A_RS18655 (U14A_03591) argD 3723433..3724653 (-) 1221 WP_000963794.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  U14A_RS18660 (U14A_03592) pabA 3724739..3725302 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  U14A_RS18665 (U14A_03593) fic 3725334..3725936 (-) 603 WP_001280613.1 putative adenosine monophosphate-protein transferase Fic -
  U14A_RS18670 (U14A_03594) yhfG 3725926..3726093 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=304005 U14A_RS18645 WP_000242755.1 3720593..3721225(+) (crp) [Escherichia coli strain U14A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=304005 U14A_RS18645 WP_000242755.1 3720593..3721225(+) (crp) [Escherichia coli strain U14A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467