Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EQO00_RS17405 Genome accession   NZ_CP035498
Coordinates   3525711..3527732 (-) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain 04-00955     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3520711..3532732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQO00_RS17370 (EQO00_17415) ybhL 3520824..3521528 (-) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -
  EQO00_RS17375 (EQO00_17420) moaE 3521665..3522117 (-) 453 WP_000852287.1 molybdopterin synthase catalytic subunit MoaE -
  EQO00_RS17380 (EQO00_17425) moaD 3522119..3522364 (-) 246 WP_000611261.1 molybdopterin synthase sulfur carrier subunit -
  EQO00_RS17385 (EQO00_17430) moaC 3522357..3522842 (-) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  EQO00_RS17390 (EQO00_17435) moaB 3522845..3523357 (-) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  EQO00_RS17395 (EQO00_17440) moaA 3523379..3524368 (-) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  EQO00_RS17400 (EQO00_17445) yvcK 3524765..3525673 (+) 909 WP_001304790.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  EQO00_RS17405 (EQO00_17450) uvrB 3525711..3527732 (-) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  EQO00_RS17410 (EQO00_17455) bioD 3528311..3528988 (-) 678 WP_000030926.1 dethiobiotin synthase -
  EQO00_RS17415 (EQO00_17460) bioC 3528981..3529736 (-) 756 WP_000246763.1 malonyl-ACP O-methyltransferase BioC -
  EQO00_RS17420 (EQO00_17465) bioF 3529723..3530877 (-) 1155 WP_000638121.1 8-amino-7-oxononanoate synthase -
  EQO00_RS17425 (EQO00_17470) bioB 3530874..3531914 (-) 1041 WP_000951218.1 biotin synthase BioB -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=303920 EQO00_RS17405 WP_000042533.1 3525711..3527732(-) (uvrB) [Escherichia coli strain 04-00955]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=303920 EQO00_RS17405 WP_000042533.1 3525711..3527732(-) (uvrB) [Escherichia coli strain 04-00955]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCGGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGACCTTCAGCGCCCAACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGCTGTATGGCGAAATGAAAGAATTC
TTTCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAGGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTAAACGAACATATCGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGCCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGTATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATATGCTCGTAATGATCAAGC
ATTCCAGCGTGGTACTTTCCGTGTTCGTGGCGAGGTGATTGATATCTTCCCGGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTGACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCACGCGAGCGCATCGTCCAGGCGATGGAGGAGATCAAAGAAGAGCT
GGCCGCCAGACGTAAAGTGCTATTGGAAAACAACAAACTGCTGGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTAGGCTACTGTTCGGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGTTGGTCGTCGATGAATCTCACGTCACCATTCCACAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACACTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCCGGTGGCGATGTGGTGGATCAGGTGGTGCGTCCAACAGGCTTACTCGACCCGATTATCGAAGTGCGGCC
AGTGGCAACACAGGTGGATGATCTTCTTTCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGGATGGCGGAAGATCTCACTGAATATCTCGAAGAACACGGTGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGTGAGTTCGACGTATTGGTAGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAAGTTTCGCTGGTGGCGATCCTCGACGCTGACAAAGAAGGCTTCCTGCGTTCCGAACGTT
CGTTGATCCAGACCATTGGTCGTGCGGCACGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCATCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATCCTGGCGCTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGCCCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTACAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557