Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EUJ32_RS20625 Genome accession   NZ_CP035486
Coordinates   4212103..4212693 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain NissleGFP_pZE21     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4207103..4217693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EUJ32_RS20610 (EUJ32_20610) uhpT 4207743..4209134 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EUJ32_RS20615 (EUJ32_20615) uhpC 4209272..4210591 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EUJ32_RS20620 (EUJ32_20620) uhpB 4210601..4212103 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EUJ32_RS20625 (EUJ32_20625) letA 4212103..4212693 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EUJ32_RS20635 (EUJ32_20635) - 4213108..4213968 (+) 861 WP_001259006.1 DUF6708 domain-containing protein -
  EUJ32_RS20640 (EUJ32_20640) ilvN 4214159..4214449 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EUJ32_RS20645 (EUJ32_20645) ilvB 4214453..4216141 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  EUJ32_RS20650 (EUJ32_20650) ivbL 4216247..4216345 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  EUJ32_RS25150 ysdE 4216590..4216664 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=303844 EUJ32_RS20625 WP_000633668.1 4212103..4212693(-) (letA) [Escherichia coli strain NissleGFP_pZE21]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=303844 EUJ32_RS20625 WP_000633668.1 4212103..4212693(-) (letA) [Escherichia coli strain NissleGFP_pZE21]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGTTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378