Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   U12A_RS23015 Genome accession   NZ_CP035476
Coordinates   4108166..4108756 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain U12A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4103166..4113756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U12A_RS23000 (U12A_03946) uhpT 4103806..4105197 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  U12A_RS23005 (U12A_03947) uhpC 4105335..4106654 (-) 1320 WP_001296565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  U12A_RS23010 (U12A_03948) uhpB 4106664..4108166 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  U12A_RS23015 (U12A_03949) letA 4108166..4108756 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  U12A_RS28560 (U12A_03950) - 4109240..4110100 (+) 861 Protein_3977 DUF6708 domain-containing protein -
  U12A_RS23025 (U12A_03952) ilvN 4110166..4110456 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  U12A_RS23030 (U12A_03953) ilvB 4110460..4112148 (-) 1689 WP_000168502.1 acetolactate synthase large subunit -
  U12A_RS23035 ivbL 4112254..4112352 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  U12A_RS27900 ysdE 4112597..4112671 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=303668 U12A_RS23015 WP_000633668.1 4108166..4108756(-) (letA) [Escherichia coli strain U12A]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=303668 U12A_RS23015 WP_000633668.1 4108166..4108756(-) (letA) [Escherichia coli strain U12A]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCTGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACAGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378