Detailed information NTG0303587

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT44_RS07190
• Genome accession: NZ_CP035455
• Coordinates: 1383863..1384864 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain emm197
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1378863..1389864

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT44_RS07175 (ETT44_07170)	thrS	1379033..1380976 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
ETT44_RS07180 (ETT44_07175)	-	1381398..1382732 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ETT44_RS07185 (ETT44_07180)	-	1382734..1383732 (-)	999	WP_002994184.1	glycosyltransferase family 4 protein	-
ETT44_RS07190 (ETT44_07185)	ccpA	1383863..1384864 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT44_RS07195 (ETT44_07190)	-	1385038..1386123 (+)	1086	WP_011054264.1	aminopeptidase P family protein	-
ETT44_RS07200 (ETT44_07195)	-	1386172..1386837 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ETT44_RS07205 (ETT44_07200)	-	1386848..1387225 (+)	378	WP_002985686.1	VOC family protein	-
ETT44_RS07210 (ETT44_07205)	-	1387370..1388296 (+)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ETT44_RS07215 (ETT44_07210)	-	1388507..1389190 (+)	684	WP_014635345.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=303587 ETT44_RS07190 WP_002985680.1 1383863..1384864(-) (ccpA) [Streptococcus pyogenes strain emm197]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=303587 ETT44_RS07190 WP_002985680.1 1383863..1384864(-) (ccpA) [Streptococcus pyogenes strain emm197]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559