Detailed information NTG0302928

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ETT51_RS08840
• Genome accession: NZ_CP035448
• Coordinates: 1761916..1764471 (-)
• Length: 851 a.a.
• NCBI ID: WP_023609835.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm70
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1756916..1769471

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT51_RS08820 (ETT51_08975)	-	1757406..1757966 (-)	561	WP_136276054.1	DNA-3-methyladenine glycosylase I	-
ETT51_RS08825 (ETT51_08980)	ruvA	1757976..1758572 (-)	597	WP_063632442.1	Holliday junction branch migration protein RuvA	Machinery gene
ETT51_RS08830 (ETT51_08985)	-	1758574..1759794 (-)	1221	WP_032461237.1	MDR family MFS transporter	-
ETT51_RS08835 (ETT51_08990)	hexB	1759805..1761787 (-)	1983	WP_032467064.1	DNA mismatch repair endonuclease MutL	Machinery gene
ETT51_RS08840 (ETT51_08995)	hexA	1761916..1764471 (-)	2556	WP_023609835.1	DNA mismatch repair protein MutS	Machinery gene
ETT51_RS09580	-	1764458..1764813 (-)	356	Protein_1674	YlbF family regulator	-
ETT51_RS08850 (ETT51_09005)	argR	1764810..1765247 (-)	438	WP_002982171.1	arginine repressor	-
ETT51_RS08855 (ETT51_09010)	argS	1765538..1767229 (+)	1692	WP_023609834.1	arginine--tRNA ligase	-
ETT51_RS08860 (ETT51_09015)	-	1767317..1767625 (+)	309	WP_012561077.1	bacteriocin immunity protein	-
ETT51_RS08865 (ETT51_09020)	-	1767652..1768524 (-)	873	WP_002982164.1	YitT family protein	-
ETT51_RS08870 (ETT51_09025)	-	1768567..1769445 (-)	879	WP_002991372.1	YitT family protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95532.08 Da
• Isoelectric Point: 4.9823

>NTDB_id=302928 ETT51_RS08840 WP_023609835.1 1761916..1764471(-) (hexA) [Streptococcus pyogenes strain emm70]
MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKIVNDIDNLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPEHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFN
DNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPPQV
ESSSAVRQGQLSLFGDDEKAHEIRQALEAIDVMNMTPFQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=302928 ETT51_RS08840 WP_023609835.1 1761916..1764471(-) (hexA) [Streptococcus pyogenes strain emm70]
ATGGCAAAAACTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTACGAGGACGCTGTCAAAGCAGCACAACTCTTAGAAATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCTATGGCAGGCGTGCCACATCATTCTGCCCAACAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTATCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGCCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCA
TTGGTTCACTATGAGATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTTTAGATTTGGTAGAAAATGCTAG
GACTAATAAAAAACATGGAAGTCTCTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACCGATTTAAGCAATAGTTTAAAAGGTGTTTACGACATCGAACGCTTATCTAGTCGCGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCTCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTGACA
GTCCTTGTGTTGACAAAATTGTCAATGATATTGACAATTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGAATTCAAATCTTAGCTTAGTTCCCGAGCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAATTTTGGCAACGGTAGATGTTTTGCAAAGTTTAGCAGTCGTTGCTGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTACAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTGACCAACAGACCAGTATTCAGCTGATTACAGGTCCAAATATGAGTGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCCCAGATGGGTTCATTTGTGGCTGCTGACCATGTTGATTTACCTTTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCCGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGCGCAAGTGACAACTCTCTTATTCTATTTGATGAACTGGGACGAGGTACGGCAACTTATGATGGTATGG
CTTTAGCCCAGGCAATTATTGAATATATCCATGATAGAGTTGGTGCTAAGACCATATTTGCAACGCATTATCATGAATTG
ACAGATTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTTACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTTGCAAAAATAGCAGGACTGCCAAAATCCCTAT
TAAAGAGAGCAGACGAAGTTCTGACCCGTTTAGAAACACAGTCACGATCTACTGAGATAATGTCAGTCCCTCCACAAGTT
GAGTCAAGCAGCGCTGTTAGACAGGGGCAATTATCCCTTTTTGGTGATGATGAGAAAGCTCATGAGATTAGGCAAGCACT
GGAAGCTATTGATGTCATGAACATGACCCCGTTTCAAGCAATGACAACTCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.445	100	0.714
mutS	Pseudomonas stutzeri strain ATCC 17587	37.076	100	0.373