Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ETT51_RS08835 Genome accession   NZ_CP035448
Coordinates   1759805..1761787 (-) Length   660 a.a.
NCBI ID   WP_032467064.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm70     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1754805..1766787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT51_RS08810 (ETT51_08965) recA 1754841..1755977 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT51_RS08815 (ETT51_08970) cinA 1756066..1757337 (-) 1272 WP_002992182.1 competence/damage-inducible protein A Machinery gene
  ETT51_RS08820 (ETT51_08975) - 1757406..1757966 (-) 561 WP_136276054.1 DNA-3-methyladenine glycosylase I -
  ETT51_RS08825 (ETT51_08980) ruvA 1757976..1758572 (-) 597 WP_063632442.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT51_RS08830 (ETT51_08985) - 1758574..1759794 (-) 1221 WP_032461237.1 MDR family MFS transporter -
  ETT51_RS08835 (ETT51_08990) hexB 1759805..1761787 (-) 1983 WP_032467064.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT51_RS08840 (ETT51_08995) hexA 1761916..1764471 (-) 2556 WP_023609835.1 DNA mismatch repair protein MutS Machinery gene
  ETT51_RS09580 - 1764458..1764813 (-) 356 Protein_1674 YlbF family regulator -
  ETT51_RS08850 (ETT51_09005) argR 1764810..1765247 (-) 438 WP_002982171.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74285.86 Da        Isoelectric Point: 5.8700

>NTDB_id=302927 ETT51_RS08835 WP_032467064.1 1759805..1761787(-) (hexB) [Streptococcus pyogenes strain emm70]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITVEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTTKKMLVISNADLDFEVSGYVSLP
ELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAVDNSIKVEK
AELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLTRLENEGQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=302927 ETT51_RS08835 WP_032467064.1 1759805..1761787(-) (hexB) [Streptococcus pyogenes strain emm70]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCGTTGAAATTGAAGAGTCTGGCCTTAAGA
TGATACAGGTTACAGACAACGGTGAGGGAATGTCTCATGAAGATTTACCTTTAAGTCTGCGTCGCCACGCTACTAGTAAA
ATTAAGAGTCAGAGTGATTTGTTTAGAATTAGAACACTTGGCTTCCGTGGAGAGGCTTTACCGTCTGTTGCCTCTATCAG
TAAAATCACGATAAAAACAGCAACAAAAGAAGTCACTCACGGTTCTCTTCTTATAGCTACTGGTGGGGAAATTGAGACAC
TTGAAGCGATCTCAACTCCTACTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACGCCTGCTCGTCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAACCGGTTGAGTTTGGCACATCCAGAAGTTGCTTT
CACACTGATTAGTGATGGTCGCCAATTAACTCAGACATCAGGAACTGGCGATTTACGCCAAGCAATTGCAGGGATTTATG
GTTTGAATACTACCAAAAAAATGCTGGTTATCTCTAATGCTGATTTGGATTTTGAAGTTTCCGGCTATGTTAGCTTGCCA
GAGTTGACACGCGCCAACCGTAATTACATGACGATTTTGGTTAATGGGCGTTACATCAAGAATTTCTTGCTTAATCGAGC
AATTCTTGATGGTTACGGTTCTAAGCTCATGGTTGGACGTTTCCCAATTGTTGTGATTGATATTCAGATTGATCCCTATT
TGGCCGATGTCAATGTTCATCCCACAAAACAAGAGGTTCGTATTTCAAAAGAGCGTGAATTAATGGCTTTAATTAGCACG
GCTATTTCAGAGAGTCTTAAGGAACAAGATTTGATTCCAGATGCTCTGGAAAACTTAGCCAAGTCAAGCACACGACATTT
CTCTAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTATTATGATCCTCAAAAGAATGACTTTTTTGTCA
AAGAGTCGGCTGTTTCTGAAAAAATACCTGAGACTGATTTTTACTCCGGCGCTGTTGACAACAGTATAAAGGTTGAAAAA
GCAGAGCTGTTACCCCACTCAGAAGAAGTTATAGGACCTTCTTCGGTTAAACACGCAAGTCGTCCCCAGAATACCTTTAC
CGAGACTGATCATCCTAATCTTGACTTAAAAAACAGACAAAAGTTATCTCAAATGCTAACCCGTTTGGAAAATGAAGGGC
AATCAGTGTTTCCCGAATTGGATTATTTTGGTCAGATGCATGGGACTTATCTCTTTGCTCAAGGTAAAGATGGCTTATTT
ATTATCGATCAGCATGCTGCTCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATTGGCGACGTTGACAGTAGTTT
ACAGCAGCTATTGGTACCCTATTTGTTTGAGTTTTCTGGTTCTGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCTTAGAAGTTTATGGGCACAATACTTTCATTTTGAGGGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTGCTTCTAACCAATGAGGTATCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTGGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTATTGATTAATTTTAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGAATTCAAGAAAATCACACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

66.867

100

0.673

Multiple sequence alignment