Detailed information NTG0302770

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ETT52_RS02265
• Genome accession: NZ_CP035447
• Coordinates: 412046..413047 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A0H2UU49
• Organism: Streptococcus pyogenes strain emm97.1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 407046..418047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT52_RS02240 (ETT52_02235)	-	407720..408403 (-)	684	WP_023078761.1	DUF969 domain-containing protein	-
ETT52_RS02245 (ETT52_02240)	-	408614..409540 (-)	927	WP_032464862.1	glycosyltransferase family 2 protein	-
ETT52_RS02250 (ETT52_02245)	-	409685..410062 (-)	378	WP_020904973.1	VOC family protein	-
ETT52_RS02255 (ETT52_02250)	-	410073..410738 (-)	666	WP_136026234.1	NAD(P)H-dependent oxidoreductase	-
ETT52_RS02260 (ETT52_02255)	-	410787..411872 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
ETT52_RS02265 (ETT52_02260)	ccpA	412046..413047 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ETT52_RS02270 (ETT52_02265)	-	413178..414176 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ETT52_RS02275 (ETT52_02270)	-	414178..415512 (+)	1335	WP_032460075.1	glycosyltransferase family 4 protein	-
ETT52_RS02280 (ETT52_02275)	thrS	415934..417877 (+)	1944	WP_128888405.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=302770 ETT52_RS02265 WP_002985680.1 412046..413047(+) (ccpA) [Streptococcus pyogenes strain emm97.1]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=302770 ETT52_RS02265 WP_002985680.1 412046..413047(+) (ccpA) [Streptococcus pyogenes strain emm97.1]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAATGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A0H2UU49

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559