Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ETT55_RS08915 Genome accession   NZ_CP035444
Coordinates   414093..414227 (+) Length   44 a.a.
NCBI ID   WP_231870885.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm90.5     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 409093..419227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT55_RS02230 (ETT55_02230) - 410133..410708 (+) 576 WP_009880369.1 uracil-DNA glycosylase family protein -
  ETT55_RS02235 (ETT55_02235) ybeY 410867..411364 (+) 498 WP_002985748.1 rRNA maturation RNase YbeY -
  ETT55_RS02240 (ETT55_02240) - 411345..411752 (+) 408 WP_030126113.1 diacylglycerol kinase family protein -
  ETT55_RS02245 (ETT55_02245) era 411872..412768 (+) 897 WP_002985743.1 GTPase Era -
  ETT55_RS02250 (ETT55_02250) - 412789..413265 (+) 477 WP_002985741.1 NUDIX hydrolase -
  ETT55_RS08910 (ETT55_02255) - 413571..413825 (-) 255 WP_111689649.1 hypothetical protein -
  ETT55_RS08915 comE/blpR 414093..414227 (+) 135 WP_231870885.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  ETT55_RS08920 - 414533..416115 (-) 1583 Protein_382 ABC transporter transmembrane domain-containing protein -
  ETT55_RS02280 (ETT55_02280) - 416413..416637 (+) 225 WP_002994580.1 Blp family class II bacteriocin -
  ETT55_RS08790 - 416615..416791 (+) 177 WP_002994581.1 hypothetical protein -
  ETT55_RS09020 (ETT55_02285) - 417123..417467 (+) 345 Protein_385 lysostaphin resistance A-like protein -
  ETT55_RS09025 - 417468..417518 (+) 51 Protein_386 bacteriocin -
  ETT55_RS02295 (ETT55_02295) - 418008..418235 (+) 228 WP_136021753.1 Blp family class II bacteriocin -
  ETT55_RS02300 (ETT55_02300) - 418284..418601 (+) 318 WP_002994587.1 hypothetical protein -

Sequence

Protein


Download         Length: 44 a.a.        Molecular weight: 5308.07 Da        Isoelectric Point: 6.9714

>NTDB_id=302556 ETT55_RS08915 WP_231870885.1 414093..414227(+) (comE/blpR) [Streptococcus pyogenes strain emm90.5]
MVLYSTRERIEFYGELSEIVKQEPRLFQCHRSFVVNPYNISSIQ

Nucleotide


Download         Length: 135 bp        

>NTDB_id=302556 ETT55_RS08915 WP_231870885.1 414093..414227(+) (comE/blpR) [Streptococcus pyogenes strain emm90.5]
TTGGTTCTTTATTCTACTAGAGAAAGGATTGAATTTTATGGGGAGTTATCTGAAATCGTTAAGCAAGAACCAAGATTATT
TCAATGCCATCGATCATTTGTTGTTAATCCCTACAATATATCTTCAATACAATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(3-44)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

62.791

97.727

0.614
  agrA Staphylococcus aureus N315

45.455

100

0.455
  comE/comE1 Streptococcus equinus JB1

41.463

93.182

0.386