Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ETT57_RS05900 Genome accession   NZ_CP035442
Coordinates   1142988..1143650 (-) Length   220 a.a.
NCBI ID   WP_136048684.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm25     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1137988..1148650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT57_RS05880 (ETT57_05870) - 1138557..1138784 (-) 228 WP_032462850.1 hypothetical protein -
  ETT57_RS05885 (ETT57_05875) sodA 1138951..1139556 (-) 606 WP_032462849.1 superoxide dismutase SodA -
  ETT57_RS05890 (ETT57_05880) holA 1139653..1140693 (-) 1041 WP_011888795.1 DNA polymerase III subunit delta -
  ETT57_RS05895 (ETT57_05885) comEC/celB 1140764..1143007 (-) 2244 WP_136048685.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ETT57_RS05900 (ETT57_05890) comEA/celA/cilE 1142988..1143650 (-) 663 WP_136048684.1 ComEA family DNA-binding protein Machinery gene
  ETT57_RS05905 (ETT57_05895) - 1143850..1144590 (-) 741 WP_002989170.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ETT57_RS05910 (ETT57_05900) - 1144708..1145484 (+) 777 WP_136048683.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ETT57_RS05915 (ETT57_05905) - 1145474..1145752 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  ETT57_RS05920 (ETT57_05910) - 1145776..1147776 (-) 2001 WP_136048682.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24614.46 Da        Isoelectric Point: 6.7451

>NTDB_id=302328 ETT57_RS05900 WP_136048684.1 1142988..1143650(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm25]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLMLSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=302328 ETT57_RS05900 WP_136048684.1 1142988..1143650(-) (comEA/celA/cilE) [Streptococcus pyogenes strain emm25]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATGCTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAGCAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405
  comEA Streptococcus thermophilus LMD-9

38.318

97.273

0.373