Detailed information NTG0302327

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ETT57_RS05895
• Genome accession: NZ_CP035442
• Coordinates: 1140764..1143007 (-)
• Length: 747 a.a.
• NCBI ID: WP_136048685.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm25
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1135764..1148007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT57_RS05865 (ETT57_05855)	-	1136403..1137623 (+)	1221	WP_136048686.1	DUF3114 domain-containing protein	-
ETT57_RS05870 (ETT57_05860)	-	1137737..1138410 (-)	674	Protein_1082	serine hydrolase	-
ETT57_RS05880 (ETT57_05870)	-	1138557..1138784 (-)	228	WP_032462850.1	hypothetical protein	-
ETT57_RS05885 (ETT57_05875)	sodA	1138951..1139556 (-)	606	WP_032462849.1	superoxide dismutase SodA	-
ETT57_RS05890 (ETT57_05880)	holA	1139653..1140693 (-)	1041	WP_011888795.1	DNA polymerase III subunit delta	-
ETT57_RS05895 (ETT57_05885)	comEC/celB	1140764..1143007 (-)	2244	WP_136048685.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ETT57_RS05900 (ETT57_05890)	comEA/celA/cilE	1142988..1143650 (-)	663	WP_136048684.1	ComEA family DNA-binding protein	Machinery gene
ETT57_RS05905 (ETT57_05895)	-	1143850..1144590 (-)	741	WP_002989170.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ETT57_RS05910 (ETT57_05900)	-	1144708..1145484 (+)	777	WP_136048683.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
ETT57_RS05915 (ETT57_05905)	-	1145474..1145752 (+)	279	WP_002989164.1	GIY-YIG nuclease family protein	-
ETT57_RS05920 (ETT57_05910)	-	1145776..1147776 (-)	2001	WP_136048682.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85541.36 Da
• Isoelectric Point: 9.6593

>NTDB_id=302327 ETT57_RS05895 WP_136048685.1 1140764..1143007(-) (comEC/celB) [Streptococcus pyogenes strain emm25]
MTFSWTKLVPLSKIQFAFLILVFFYQIHSPSWLTFLLSLSLICLLVKRLSKKEFLGVFAILSFCALFLLYQKQQLIQKLE
IQPVQITSVALVPDSIRINGDQLAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
FLTYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLFDLFILPLL
CLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLILVISFAIFYDYRQVRQRVITCGLVIALTLLS
VKYPLTNEVTFIDIGQGDSIVVREWTGKNLLIDVGGRSFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHAD
TDHMGDIEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPWQLGDGKNNDSLVLYGR
LLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTSSSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=302327 ETT57_RS05895 WP_136048685.1 1140764..1143007(-) (comEC/celB) [Streptococcus pyogenes strain emm25]
ATGACATTTTCTTGGACTAAGCTAGTGCCCCTGTCAAAGATTCAATTTGCTTTTTTAATCTTGGTTTTCTTTTATCAAAT
CCATAGCCCTAGCTGGTTAACGTTTCTCCTTAGCCTTAGTTTGATTTGCTTACTTGTCAAGCGTTTGTCTAAAAAAGAAT
TTCTCGGTGTCTTTGCCATCCTTAGTTTCTGTGCTTTGTTTTTGCTGTATCAGAAACAGCAGTTGATTCAAAAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGCATTAGTTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTCTTGG
ACGTCACGGGAAACATTCTTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAGAAAGAGCACC
GTTGGTTAGTGATGCACGCAAAAGTGACATTGGAAAAAGCTGAGGAAGTTCGAAATTTTAAAGGCTTTAATTATCAGACT
TTTTTGACTTATCAAGGAATTTACAGGATAGGGAAGGTAGAGCAAATAGAACAGCTTGAAGTGATTTCACCCGAGTCAAT
ATGTGACTATTTGTCCTCTTTAAGACGACGAGCCATTGTTCATTGCCAGCAGCATTTTCCAAGACCTATGTCTCACTACC
TGACGGGCCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGTCAGTTGGGTATCATTCAT
CTCTTTGCTTTATCAGGGATGCAGGTTGGCTTCTTTCTCACTTGTTTTAGAAGGGTGTTGCTATTACTCGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGTTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGAATAAAAGGATTAGACAATCTGGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCTCATTTCTTAATGACTGTTGGTGGCGTATTAACGTTTAGCTATGCTTTTTTGTTAACAGTGGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGTCTTGACCATTTCCCTAGGAATATTACCATTTTTGCTCTTTTATT
TTTCCAGTTTTAACCCCATGTCAATGGTCTTAACAGGGCTCTTGTCTTATCTCTTTGACCTTTTTATTTTGCCCCTTCTT
TGTCTGGTTTTTTGTCTATCACCTTTGGTGACTGTCTCAATATGTAACCATCTTTTTATTTTATTAGAAAAAGTCATTCA
ATTTCTCGGAAATACTTTCAATAGTTCCCTTGTTTTTGGAAGCCCGACCAGTTGGCACTTGCTTATCTTGGTGATTAGCT
TCGCTATTTTTTATGATTATCGGCAGGTGCGACAACGAGTTATCACTTGCGGTTTGGTTATAGCGTTGACGCTTTTGTCT
GTCAAATATCCTTTGACCAATGAAGTGACCTTTATCGACATTGGCCAGGGAGATAGTATTGTGGTGAGGGAGTGGACAGG
GAAAAATCTCTTAATAGATGTAGGTGGGCGCTCTTTCTTTTCTTCAAAAGAGCACTGGCGACGAGGACATCACGTAGCTA
ATGCTCAGAAAACCTTAATTCCTTACTTAAAAAGTAGAGGTATTCACACAATTGACCAACTATTAGTAACTCACGCAGAT
ACTGATCATATGGGGGATATCGAAGTGGTTGCCAAAGCTATTCGGATAAAGGAGATTTTGACTAGTCAAGGCAGTTTAAG
CCATCCAAGCTTTGTTAGGCGGCTAAGGCGTTTAAAATGTCACGTTAGGGTTTTAGCAGCTGGAGACCAGTTGCCTATTA
TGGGAAGTGTCTTACAGGTACTCTACCCTTGGCAGTTAGGGGACGGGAAAAATAACGATTCTTTGGTACTCTATGGCAGG
CTCTTAAATCGAACTTTTCTTTTCACAGGTGACTTGGAAAAAGAGGGGGAAAACGAGATCATAAAACGTTATCCTCAACT
AAGAGTAGATTATTTAAAAGCAGGTCACCATGGATCAAATACCTCTTCTAGTGCAGCTTTTTTAGACCATATTCAGCCTA
AAGTTGCCTTTATTTCTGCTGGAAAAAATAACCGTTATCAGCATCCTCACAGAGAAACCTTAGCCCGTTTGGAAGACAGA
CAAATTACTTATTACCGAACGGATACACAAGGAGCTATTCGTTTGACTGGTTGGACAAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-701)

• Competence protein (Competence) (217-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	46.185	100	0.462
comEC/celB	Streptococcus mitis NCTC 12261	45.979	99.866	0.459
comEC/celB	Streptococcus pneumoniae TIGR4	44.98	100	0.45
comEC/celB	Streptococcus pneumoniae Rx1	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae D39	44.786	100	0.448
comEC/celB	Streptococcus pneumoniae R6	44.786	100	0.448
comEC	Lactococcus lactis subsp. cremoris KW2	41.632	95.181	0.396