Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ETT59_RS08540 Genome accession   NZ_CP035440
Coordinates   1708780..1709376 (-) Length   198 a.a.
NCBI ID   WP_136305971.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1703780..1714376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS08505 (ETT59_08500) - 1703840..1704145 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ETT59_RS08510 (ETT59_08505) ruvX 1704157..1704576 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ETT59_RS08515 (ETT59_08510) - 1704573..1704842 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ETT59_RS08520 (ETT59_08515) spx 1704956..1705354 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ETT59_RS08525 (ETT59_08520) recA 1705645..1706781 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  ETT59_RS08530 (ETT59_08525) cinA 1706870..1708141 (-) 1272 WP_032459984.1 competence/damage-inducible protein A Machinery gene
  ETT59_RS08535 (ETT59_08530) - 1708210..1708770 (-) 561 WP_023611248.1 DNA-3-methyladenine glycosylase I -
  ETT59_RS08540 (ETT59_08535) ruvA 1708780..1709376 (-) 597 WP_136305971.1 Holliday junction branch migration protein RuvA Machinery gene
  ETT59_RS08545 (ETT59_08540) - 1709378..1710598 (-) 1221 WP_002991361.1 MFS transporter -
  ETT59_RS08550 (ETT59_08545) hexB 1710609..1712591 (-) 1983 WP_136267866.1 DNA mismatch repair endonuclease MutL Machinery gene
  ETT59_RS08555 (ETT59_08550) - 1712686..1713831 (-) 1146 WP_002992191.1 site-specific integrase -
  ETT59_RS08560 (ETT59_08555) - 1714159..1714302 (+) 144 WP_002992192.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21825.19 Da        Isoelectric Point: 6.7342

>NTDB_id=302170 ETT59_RS08540 WP_136305971.1 1708780..1709376(-) (ruvA) [Streptococcus pyogenes strain emm124]
MYDYIKGQLTKITAKYIVVETKGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=302170 ETT59_RS08540 WP_136305971.1 1708780..1709376(-) (ruvA) [Streptococcus pyogenes strain emm124]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAAGGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment