Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ETT66_RS04070 Genome accession   NZ_CP035433
Coordinates   799024..801015 (+) Length   663 a.a.
NCBI ID   WP_136275114.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm65     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 794024..806015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT66_RS04055 (ETT66_04055) - 794241..795620 (+) 1380 WP_136286261.1 PTS sugar transporter subunit IIC -
  ETT66_RS09000 - 795617..795769 (+) 153 WP_003062002.1 hypothetical protein -
  ETT66_RS04060 (ETT66_04060) - 795917..796657 (-) 741 WP_002984187.1 amino acid ABC transporter ATP-binding protein -
  ETT66_RS04065 (ETT66_04065) - 796657..798831 (-) 2175 WP_136286260.1 ABC transporter substrate-binding protein/permease -
  ETT66_RS04070 (ETT66_04070) uvrB 799024..801015 (+) 1992 WP_136275114.1 excinuclease ABC subunit UvrB Machinery gene
  ETT66_RS04075 (ETT66_04075) - 801279..801422 (+) 144 WP_002984200.1 teichoic acid D-Ala incorporation-associated protein DltX -
  ETT66_RS04080 (ETT66_04080) dltA 801434..802972 (+) 1539 WP_002984203.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  ETT66_RS04085 (ETT66_04085) dltB 802969..804225 (+) 1257 WP_002994626.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  ETT66_RS04090 (ETT66_04090) dltC 804243..804482 (+) 240 WP_136286259.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  ETT66_RS04095 (ETT66_04095) dltD 804475..805725 (+) 1251 WP_002984219.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75664.72 Da        Isoelectric Point: 4.6420

>NTDB_id=301475 ETT66_RS04070 WP_136275114.1 799024..801015(+) (uvrB) [Streptococcus pyogenes strain emm65]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQIFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=301475 ETT66_RS04070 WP_136275114.1 799024..801015(+) (uvrB) [Streptococcus pyogenes strain emm65]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGATATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

UvrB/uvrC motif (UVR)

(627-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.068

100

0.851
  uvrB Streptococcus pneumoniae D39

85.068

100

0.851
  uvrB Streptococcus pneumoniae TIGR4

84.917

100

0.849