Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ETT67_RS05350 Genome accession   NZ_CP035432
Coordinates   1042818..1044809 (-) Length   663 a.a.
NCBI ID   WP_002989569.1    Uniprot ID   P0DH39
Organism   Streptococcus pyogenes strain emm11     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1037818..1049809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT67_RS05325 (ETT67_05315) dltD 1038108..1039358 (-) 1251 WP_011017899.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  ETT67_RS05330 (ETT67_05320) dltC 1039351..1039590 (-) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  ETT67_RS05335 (ETT67_05325) dltB 1039608..1040864 (-) 1257 WP_002994626.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  ETT67_RS05340 (ETT67_05330) dltA 1040861..1042399 (-) 1539 WP_023079019.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  ETT67_RS05345 (ETT67_05335) - 1042411..1042554 (-) 144 WP_023079026.1 teichoic acid D-Ala incorporation-associated protein DltX -
  ETT67_RS05350 (ETT67_05340) uvrB 1042818..1044809 (-) 1992 WP_002989569.1 excinuclease ABC subunit UvrB Machinery gene
  ETT67_RS05355 (ETT67_05345) - 1045002..1047176 (+) 2175 WP_002989566.1 ABC transporter substrate-binding protein/permease -
  ETT67_RS05360 (ETT67_05350) - 1047176..1047916 (+) 741 WP_002984187.1 amino acid ABC transporter ATP-binding protein -
  ETT67_RS09210 - 1048064..1048216 (-) 153 WP_023079022.1 hypothetical protein -
  ETT67_RS05365 (ETT67_05355) - 1048213..1049592 (-) 1380 WP_136019790.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75664.72 Da        Isoelectric Point: 4.6420

>NTDB_id=301378 ETT67_RS05350 WP_002989569.1 1042818..1044809(-) (uvrB) [Streptococcus pyogenes strain emm11]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=301378 ETT67_RS05350 WP_002989569.1 1042818..1044809(-) (uvrB) [Streptococcus pyogenes strain emm11]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTGTCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTAGAATTTTTTGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGATCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAATCAGCGCGTAGCGCGTGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTCCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

UvrB/uvrC motif (UVR)

(627-660)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0DH39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

85.068

100

0.851
  uvrB Streptococcus pneumoniae D39

85.068

100

0.851
  uvrB Streptococcus pneumoniae TIGR4

84.917

100

0.849