Detailed information NTG0301297

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: DRF63_RS09615
• Genome accession: NZ_CP030753
• Coordinates: 2037300..2037956 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain S4074
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2032300..2042956

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DRF63_RS09595 (DRF63_09590)	nanA	2032674..2033552 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
DRF63_RS09600 (DRF63_09595)	nagB	2033602..2034405 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
DRF63_RS09605 (DRF63_09600)	nagA	2034457..2035602 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
DRF63_RS09610 (DRF63_09605)	fumC	2035751..2037145 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
DRF63_RS09615 (DRF63_09610)	sxy/tfoX	2037300..2037956 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
DRF63_RS09620 (DRF63_09615)	rpsJ	2038364..2038675 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
DRF63_RS09625 (DRF63_09620)	rplC	2038701..2039327 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
DRF63_RS09630 (DRF63_09625)	rplD	2039343..2039945 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
DRF63_RS09635 (DRF63_09630)	rplW	2039942..2040247 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
DRF63_RS09640 (DRF63_09635)	rplB	2040268..2041089 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
DRF63_RS09645 (DRF63_09640)	rpsS	2041117..2041392 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
DRF63_RS09650 (DRF63_09645)	rplV	2041403..2041735 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
DRF63_RS09655 (DRF63_09650)	rpsC	2041754..2042461 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
DRF63_RS09660 (DRF63_09655)	rplP	2042475..2042885 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=301297 DRF63_RS09615 WP_005609196.1 2037300..2037956(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain S4074]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=301297 DRF63_RS09615 WP_005609196.1 2037300..2037956(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain S4074]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376