Detailed information NTG0300422

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DQ228_RS03100
• Genome accession: NZ_CP030250
• Coordinates: 580872..581873 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain CS20
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 575872..586873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQ228_RS03080	smpB	576977..577441 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
DQ228_RS03085	-	577595..579001 (+)	1407	WP_087009785.1	Cof-type HAD-IIB family hydrolase	-
DQ228_RS03090	-	579003..579368 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
DQ228_RS03095	-	579471..580556 (-)	1086	WP_011225703.1	M24 family metallopeptidase	-
DQ228_RS03100	ccpA	580872..581873 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
DQ228_RS03105	-	581933..582130 (+)	198	WP_100284894.1	MmcQ family protein	-
DQ228_RS03110	-	582236..582460 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
DQ228_RS03115	-	582461..583000 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
DQ228_RS03120	-	583013..584128 (+)	1116	WP_011680937.1	glycerate kinase	-
DQ228_RS03125	-	584175..584630 (-)	456	WP_232979714.1	YueI family protein	-
DQ228_RS03130	eno	584839..586143 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
DQ228_RS03135	-	586296..586480 (-)	185	Protein_586	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=300422 DQ228_RS03100 WP_004197422.1 580872..581873(+) (ccpA) [Streptococcus thermophilus strain CS20]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=300422 DQ228_RS03100 WP_004197422.1 580872..581873(+) (ccpA) [Streptococcus thermophilus strain CS20]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGATGTT
ATCCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547