Detailed information NTG0030038

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPH_RS10480
• Genome accession: NC_010380
• Coordinates: 1975072..1976082 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990606.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae Hungary19A-6
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1970072..1981082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPH_RS10455 (SPH_2137)	-	1971373..1971666 (-)	294	WP_000977364.1	hypothetical protein	-
SPH_RS10460 (SPH_2138)	-	1971828..1972280 (+)	453	WP_000079148.1	universal stress protein	-
SPH_RS10465 (SPH_2139)	-	1972315..1973676 (-)	1362	WP_029645285.1	Cof-type HAD-IIB family hydrolase	-
SPH_RS10470 (SPH_2141)	-	1973768..1974730 (+)	963	WP_001124778.1	asparaginase	-
SPH_RS10475 (SPH_2140)	-	1974727..1975008 (-)	282	WP_001092034.1	hypothetical protein	-
SPH_RS10480 (SPH_2142)	ccpA	1975072..1976082 (-)	1011	WP_000990606.1	catabolite control protein A	Regulator
SPH_RS10485 (SPH_2143)	-	1976507..1977106 (-)	600	WP_000866696.1	response regulator transcription factor	-
SPH_RS10490 (SPH_2144)	-	1977108..1978205 (-)	1098	WP_000893517.1	sensor histidine kinase	-
SPH_RS10495 (SPH_2145)	-	1978205..1978942 (-)	738	WP_000832839.1	ABC transporter permease	-
SPH_RS10500 (SPH_2146)	-	1978944..1979828 (-)	885	WP_000219353.1	ABC transporter ATP-binding protein	-
SPH_RS10505 (SPH_2147)	-	1979815..1980009 (-)	195	WP_000820185.1	hypothetical protein	-
SPH_RS10510 (SPH_2148)	-	1980006..1980212 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37042.99 Da
• Isoelectric Point: 5.3212

>NTDB_id=30038 SPH_RS10480 WP_000990606.1 1975072..1976082(-) (ccpA) [Streptococcus pneumoniae Hungary19A-6]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=30038 SPH_RS10480 WP_000990606.1 1975072..1976082(-) (ccpA) [Streptococcus pneumoniae Hungary19A-6]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGCTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCGCTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.405	100	0.994
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568