Detailed information NTG0299524

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CHN55_RS04280
• Genome accession: NZ_CP030136
• Coordinates: 804201..805244 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain S57
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 799201..810244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CHN55_RS04245 (CHN55_04245)	-	799746..799856 (+)	111	WP_031775032.1	hypothetical protein	-
CHN55_RS04250 (CHN55_04250)	-	799885..800298 (+)	414	WP_001670387.1	hypothetical protein	-
CHN55_RS04260 (CHN55_04260)	-	800729..801715 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
CHN55_RS04265 (CHN55_04265)	map	802127..802885 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CHN55_RS04270 (CHN55_04270)	-	803102..803488 (+)	387	WP_001110179.1	hypothetical protein	-
CHN55_RS04275 (CHN55_04275)	liaF	803503..804204 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CHN55_RS04280 (CHN55_04280)	vraS	804201..805244 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CHN55_RS04285 (CHN55_04285)	vraR	805234..805863 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CHN55_RS04290 (CHN55_04290)	-	805975..807192 (-)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
CHN55_RS04295 (CHN55_04295)	-	807470..807745 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
CHN55_RS04300 (CHN55_04300)	-	807752..808216 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CHN55_RS04305 (CHN55_04305)	-	808363..808563 (+)	201	WP_000180460.1	DUF1128 family protein	-
CHN55_RS04310 (CHN55_04310)	-	808566..809822 (+)	1257	WP_129409662.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=299524 CHN55_RS04280 WP_001017131.1 804201..805244(+) (vraS) [Staphylococcus aureus strain S57]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=299524 CHN55_RS04280 WP_001017131.1 804201..805244(+) (vraS) [Staphylococcus aureus strain S57]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1