Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DK877_RS04000 Genome accession   NZ_CP030023
Coordinates   780251..781600 (+) Length   449 a.a.
NCBI ID   WP_009910235.1    Uniprot ID   A0A0Z8DHB7
Organism   Streptococcus suis strain ISU2414     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 775251..786600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK877_RS03975 (DK877_04100) - 776362..777021 (-) 660 WP_009910247.1 amino acid ABC transporter permease -
  DK877_RS03980 (DK877_04105) - 777036..777734 (-) 699 WP_013730248.1 amino acid ABC transporter permease -
  DK877_RS03985 (DK877_04110) - 777749..778588 (-) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  DK877_RS03990 (DK877_04115) - 778599..779360 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  DK877_RS03995 (DK877_04120) micA 779554..780258 (+) 705 WP_004298854.1 response regulator YycF Regulator
  DK877_RS04000 (DK877_04125) micB 780251..781600 (+) 1350 WP_009910235.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK877_RS04005 (DK877_04130) vicX 781607..782410 (+) 804 WP_009910233.1 MBL fold metallo-hydrolase Regulator
  DK877_RS04010 (DK877_04140) - 783147..784349 (-) 1203 Protein_745 IS110 family transposase -
  DK877_RS04015 (DK877_04145) - 784588..785043 (+) 456 WP_002935846.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51099.13 Da        Isoelectric Point: 4.5202

>NTDB_id=298482 DK877_RS04000 WP_009910235.1 780251..781600(+) (micB) [Streptococcus suis strain ISU2414]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNTDSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKTDLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=298482 DK877_RS04000 WP_009910235.1 780251..781600(+) (micB) [Streptococcus suis strain ISU2414]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAA
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGGGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATACTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAA
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGCGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8DHB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment