Detailed information NTG0298289

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: A7J09_RS11415
• Genome accession: NZ_CP030015
• Coordinates: 2372102..2372839 (-)
• Length: 245 a.a.
• NCBI ID: WP_029175141.1
• Uniprot ID: -
• Organism: Streptococcus suis strain ISU2812
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 2367102..2377839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J09_RS11385 (A7J09_11610)	-	2367729..2368259 (-)	531	WP_009910909.1	DUF1697 domain-containing protein	-
A7J09_RS11390 (A7J09_11615)	-	2368273..2368530 (-)	258	WP_013730620.1	Txe/YoeB family addiction module toxin	-
A7J09_RS11395 (A7J09_11620)	-	2368532..2368792 (-)	261	WP_002939010.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
A7J09_RS11400 (A7J09_11625)	-	2368868..2369185 (-)	318	WP_228380450.1	NUDIX domain-containing protein	-
A7J09_RS11405 (A7J09_11630)	-	2369449..2370704 (+)	1256	WP_172411187.1	ISL3 family transposase	-
A7J09_RS11410 (A7J09_11635)	-	2370748..2372088 (-)	1341	WP_029175140.1	sensor histidine kinase	-
A7J09_RS11415 (A7J09_11640)	comE/blpR	2372102..2372839 (-)	738	WP_029175141.1	response regulator transcription factor	Regulator
A7J09_RS11420 (A7J09_11645)	-	2372841..2373182 (-)	342	WP_029175142.1	LytR/AlgR family response regulator transcription factor	-
A7J09_RS11425	-	2373381..2373776 (+)	396	WP_029175143.1	hypothetical protein	-
A7J09_RS11430 (A7J09_11655)	-	2373712..2375592 (-)	1881	WP_029178621.1	SAG1250 family conjugative relaxase	-
A7J09_RS11435 (A7J09_11660)	mobC	2375579..2375944 (-)	366	WP_029174877.1	plasmid mobilization relaxosome protein MobC	-
A7J09_RS11440 (A7J09_11665)	-	2375947..2376309 (-)	363	WP_029174876.1	SAG1252 family conjugative relaxosome accessory protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28602.77 Da
• Isoelectric Point: 7.2199

>NTDB_id=298289 A7J09_RS11415 WP_029175141.1 2372102..2372839(-) (comE/blpR) [Streptococcus suis strain ISU2812]
MNIFVLEDDFKQQARIEKIITKLLEKHNIVPKKFEISGKPHQLLQAIEEKGVHQLFFLDIEIKEDELKGLQVAKQIREID
PYASIVFVTTHSEFMPLSFRYQVSALDYIDKELGVTEFESRIEAALLHTHNKDNSAVSDDSFYFKSKYAQVQYPFNEVYY
IETSPRPHRVILYTKTDRMEFTASLSDILKQDKRLVQCHRSFAINPRNVLKVDRNEKQIYFPNGATCFISRQKLESTLAA
VANLH

Nucleotide

• Length: 738 bp

>NTDB_id=298289 A7J09_RS11415 WP_029175141.1 2372102..2372839(-) (comE/blpR) [Streptococcus suis strain ISU2812]
ATGAATATCTTTGTATTGGAAGATGATTTTAAGCAACAAGCGAGAATTGAGAAGATTATTACTAAGCTGTTAGAAAAGCA
CAACATCGTTCCGAAAAAATTTGAAATTTCAGGAAAACCCCATCAGCTACTTCAAGCAATAGAAGAAAAAGGAGTACATC
AGCTCTTCTTTTTAGATATTGAGATTAAGGAAGACGAACTAAAAGGACTTCAAGTCGCTAAACAAATTAGAGAGATTGAC
CCTTATGCTAGTATTGTTTTTGTGACAACACACTCCGAGTTTATGCCCTTATCTTTCAGGTACCAGGTATCTGCCTTGGA
CTATATTGACAAAGAGCTTGGAGTTACCGAATTTGAATCGCGAATAGAAGCAGCTTTACTTCATACTCACAATAAGGACA
ATAGCGCCGTATCGGATGATTCATTCTATTTTAAGTCCAAATATGCTCAAGTACAATACCCATTCAATGAAGTGTACTAC
ATCGAGACTTCTCCCCGCCCTCATCGTGTTATCCTTTATACCAAGACAGACCGAATGGAGTTCACAGCAAGTTTGTCAGA
CATTTTGAAACAAGATAAACGACTTGTACAATGCCATCGTTCGTTTGCAATCAATCCGAGGAATGTTCTTAAAGTGGATA
GAAATGAAAAACAGATCTACTTTCCTAATGGAGCCACCTGTTTTATTTCAAGGCAAAAGCTAGAATCAACTTTAGCAGCT
GTTGCTAATCTGCACTAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-235)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.279	99.592	0.531
comE/comE1	Streptococcus equinus JB1	41.841	97.551	0.408
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367