Detailed information NTG0297787

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EQH17_RS05100
• Genome accession: NZ_CP035263
• Coordinates: 1018649..1020637 (+)
• Length: 662 a.a.
• NCBI ID: WP_000607027.1
• Uniprot ID: Q54986
• Organism: Streptococcus pneumoniae strain TVO_1901922
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1013649..1025637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH17_RS05085 (EQH17_05370)	-	1014545..1015285 (-)	741	WP_001096313.1	amino acid ABC transporter ATP-binding protein	-
EQH17_RS05090 (EQH17_05375)	-	1015285..1017450 (-)	2166	WP_000726273.1	ABC transporter substrate-binding protein/permease	-
EQH17_RS05095 (EQH17_05380)	-	1017619..1018572 (+)	954	WP_000792117.1	CPBP family intramembrane glutamic endopeptidase	-
EQH17_RS05100 (EQH17_05385)	uvrB	1018649..1020637 (+)	1989	WP_000607027.1	excinuclease ABC subunit UvrB	Machinery gene
EQH17_RS05105 (EQH17_05390)	-	1020647..1021210 (+)	564	WP_000639840.1	GNAT family N-acetyltransferase	-
EQH17_RS05110 (EQH17_05395)	-	1021176..1021664 (+)	489	WP_000216026.1	GNAT family N-acetyltransferase	-
EQH17_RS05115 (EQH17_05400)	-	1021738..1022205 (+)	468	WP_000091534.1	8-oxo-dGTP diphosphatase	-
EQH17_RS05120 (EQH17_05405)	-	1022202..1022717 (-)	516	WP_000159176.1	transcription repressor NadR	-
EQH17_RS05125 (EQH17_05410)	-	1022729..1023256 (-)	528	WP_001097402.1	ECF transporter S component	-
EQH17_RS05130 (EQH17_05415)	-	1023538..1024101 (-)	564	WP_000747408.1	ECF transporter S component	-
EQH17_RS05135 (EQH17_05420)	coaC	1024085..1024636 (-)	552	WP_001284128.1	phosphopantothenoylcysteine decarboxylase	-
EQH17_RS05140 (EQH17_05425)	coaB	1024648..1025337 (-)	690	WP_000699488.1	phosphopantothenate--cysteine ligase	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75733.76 Da
• Isoelectric Point: 4.5848

>NTDB_id=297787 EQH17_RS05100 WP_000607027.1 1018649..1020637(+) (uvrB) [Streptococcus pneumoniae strain TVO_1901922]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide

• Length: 1989 bp

>NTDB_id=297787 EQH17_RS05100 WP_000607027.1 1018649..1020637(+) (uvrB) [Streptococcus pneumoniae strain TVO_1901922]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTTCTCGACTTCTTCCCAGATGATTTCTTGATTATGATTGACGAGAGTCATAT
GACCATAGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTGGTTAATTATGGTTTCCGTTTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGATTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGTCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB/uvrC motif (UVR) (626-660)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: Q54986

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae TIGR4	100	100	1
uvrB	Streptococcus pneumoniae R6	99.849	100	0.998
uvrB	Streptococcus pneumoniae D39	99.849	100	0.998