Detailed information NTG0297715

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH18_RS09220
• Genome accession: NZ_CP035262
• Coordinates: 1844002..1844901 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904862.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1839002..1849901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS09195 (EQH18_09720)	rsmA	1839332..1840204 (-)	873	WP_001216879.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH18_RS09200 (EQH18_09725)	-	1840335..1840643 (-)	309	WP_000333257.1	hypothetical protein	-
EQH18_RS09205 (EQH18_09730)	-	1840636..1841277 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH18_RS09210 (EQH18_09735)	-	1841279..1843309 (-)	2031	WP_000825246.1	bacteriocin-associated integral membrane family protein	-
EQH18_RS09215 (EQH18_09740)	-	1843386..1843682 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
EQH18_RS09220 (EQH18_09745)	comR	1844002..1844901 (-)	900	WP_000904862.1	helix-turn-helix transcriptional regulator	Regulator
EQH18_RS09225 (EQH18_09750)	rnmV	1844973..1845533 (-)	561	WP_000660013.1	ribonuclease M5	-
EQH18_RS09230 (EQH18_09755)	-	1845533..1846306 (-)	774	WP_000575596.1	TatD family hydrolase	-
EQH18_RS09235 (EQH18_09765)	-	1846611..1847588 (-)	978	Protein_1831	DUF1542 domain-containing protein	-
EQH18_RS09240 (EQH18_09770)	rpmH	1847794..1847928 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
EQH18_RS09245 (EQH18_09775)	-	1848073..1849287 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
EQH18_RS09250 (EQH18_09780)	-	1849443..1849736 (-)	294	WP_000977363.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.16 Da
• Isoelectric Point: 4.7732

>NTDB_id=297715 EQH18_RS09220 WP_000904862.1 1844002..1844901(-) (comR) [Streptococcus pneumoniae strain TVO_1901923]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=297715 EQH18_RS09220 WP_000904862.1 1844002..1844901(-) (comR) [Streptococcus pneumoniae strain TVO_1901923]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365