Detailed information NTG0297085

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EQH23_RS05875
• Genome accession: NZ_CP035257
• Coordinates: 1183946..1185934 (-)
• Length: 662 a.a.
• NCBI ID: WP_000607033.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901928
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1178946..1190934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH23_RS05835 (EQH23_06185)	coaB	1179247..1179936 (+)	690	WP_000699494.1	phosphopantothenate--cysteine ligase	-
EQH23_RS05840 (EQH23_06190)	coaC	1179948..1180499 (+)	552	WP_001284128.1	phosphopantothenoylcysteine decarboxylase	-
EQH23_RS05845 (EQH23_06195)	-	1180483..1181046 (+)	564	WP_000747408.1	ECF transporter S component	-
EQH23_RS05850 (EQH23_06200)	-	1181328..1181855 (+)	528	WP_001097402.1	ECF transporter S component	-
EQH23_RS05855 (EQH23_06205)	-	1181867..1182382 (+)	516	WP_000159176.1	transcription repressor NadR	-
EQH23_RS05860 (EQH23_06210)	-	1182379..1182846 (-)	468	WP_000091537.1	8-oxo-dGTP diphosphatase	-
EQH23_RS05865 (EQH23_06215)	-	1182919..1183407 (-)	489	WP_000216006.1	GNAT family N-acetyltransferase	-
EQH23_RS05870 (EQH23_06220)	-	1183373..1183936 (-)	564	WP_000639842.1	GNAT family N-acetyltransferase	-
EQH23_RS05875 (EQH23_06225)	uvrB	1183946..1185934 (-)	1989	WP_000607033.1	excinuclease ABC subunit UvrB	Machinery gene
EQH23_RS05880 (EQH23_06230)	-	1186011..1186964 (-)	954	WP_000792099.1	CPBP family intramembrane glutamic endopeptidase	-
EQH23_RS05885 (EQH23_06235)	-	1187137..1189302 (+)	2166	WP_000726260.1	ABC transporter substrate-binding protein/permease	-
EQH23_RS05890 (EQH23_06240)	-	1189302..1190042 (+)	741	WP_001096339.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75867.91 Da
• Isoelectric Point: 4.5676

>NTDB_id=297085 EQH23_RS05875 WP_000607033.1 1183946..1185934(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901928]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKVLD

Nucleotide

• Length: 1989 bp

>NTDB_id=297085 EQH23_RS05875 WP_000607033.1 1183946..1185934(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901928]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAGAACTATTCACGACACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTCTTAGATTTCTTCCCAGATGATTTCTTAATTATGATTGACGAGAGTCACAT
GACCATGGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTGGTTAATTATGGCTTCCGATTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCTGAAGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGATAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGACCTATAATGAAGAGCATGA
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAGGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATTCGTGATATGATGTTGGAAGTCAAGGTCTTGGATTAG

Domains

Predicted by InterProScan.

• UvrB/uvrC motif (UVR) (626-659)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• Ultra-violet resistance protein B (UvrB) (556-598)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• UvrB interaction domain (UvrB_inter) (164-254)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	99.547	100	0.995
uvrB	Streptococcus pneumoniae D39	99.547	100	0.995
uvrB	Streptococcus pneumoniae TIGR4	99.396	100	0.994