Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EQH24_RS06135 Genome accession   NZ_CP035256
Coordinates   1207489..1209477 (-) Length   662 a.a.
NCBI ID   WP_023396309.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1202489..1214477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS06095 (EQH24_06415) coaB 1202790..1203479 (+) 690 WP_000699499.1 phosphopantothenate--cysteine ligase -
  EQH24_RS06100 (EQH24_06420) coaC 1203491..1204042 (+) 552 WP_001284124.1 phosphopantothenoylcysteine decarboxylase -
  EQH24_RS06105 (EQH24_06425) - 1204026..1204589 (+) 564 WP_000747407.1 ECF transporter S component -
  EQH24_RS06110 (EQH24_06430) - 1204871..1205398 (+) 528 WP_023396303.1 hypothetical protein -
  EQH24_RS06115 (EQH24_06435) - 1205410..1205925 (+) 516 WP_023396304.1 transcription repressor NadR -
  EQH24_RS06120 (EQH24_06440) - 1205922..1206389 (-) 468 WP_023396305.1 8-oxo-dGTP diphosphatase -
  EQH24_RS06125 (EQH24_06445) - 1206462..1206950 (-) 489 WP_023396306.1 GNAT family N-acetyltransferase -
  EQH24_RS06130 (EQH24_06450) - 1206916..1207479 (-) 564 WP_000639842.1 GNAT family N-acetyltransferase -
  EQH24_RS06135 (EQH24_06455) uvrB 1207489..1209477 (-) 1989 WP_023396309.1 excinuclease ABC subunit UvrB Machinery gene
  EQH24_RS06140 (EQH24_06460) - 1209554..1210507 (-) 954 WP_023396662.1 CPBP family intramembrane glutamic endopeptidase -
  EQH24_RS06145 (EQH24_06465) - 1210679..1212844 (+) 2166 WP_023396663.1 ABC transporter substrate-binding protein/permease -
  EQH24_RS06150 (EQH24_06470) - 1212844..1213584 (+) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75786.84 Da        Isoelectric Point: 4.5835

>NTDB_id=296961 EQH24_RS06135 WP_023396309.1 1207489..1209477(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901930]
MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQTELEEQLAVFDKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=296961 EQH24_RS06135 WP_023396309.1 1207489..1209477(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901930]
ATGATTAACCGCATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTAGATAATATCGAGGGTGGAGAAAAAGCTCAGATTCTGATGGGGGCGACCGGAACAGGGAAGACCTATACCA
TGAGTCAGGTCATTTCCAAAGTCAATAAACCCACTCTAGTCATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTCAAGGAATTTTTCCCTGAAAATGCAGTTGAGTACTTCGTATCCTACTATGACTATTACCAGCCAGAAGCCTATGT
CCCTTCTAGTGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGTCACTCAGCGACTTCAG
CCCTATTGGAGCGCAATGATGTTATTGTCGTGGCCTCGGTCTCTTGTATCTATGGTCTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCAGGTCTTGAAATTTCCCGTGATAAACTCTTGAATGACTTGGTGGATATCCAATTTGA
GCGAAATGATATTGATTTCCAACGGGGAAGATTTCGCGTTCGTGGGGATGTGGTGGAGATTTTCCCTGCTTCCCGTGATG
AACACGCTTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAGGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTGGCTATTTTCCCAGCTACTCACTTTGTGACCAATGATGACCACATGGAAGTTGCTATTGCTAA
GATTCAGACTGAGTTGGAAGAGCAACTAGCTGTCTTTGATAAGGAAGGTAAATTGCTAGAAGCCCAGCGATTGAAACAGC
GGACAGAATATGATATCGAAATGCTGCGCGAGATGGGCTATACAAATGGGGTTGAAAACTATTCACGTCACATGGATGGA
CGTAGCGAAGGTGAGCCTCCTTATACCCTTCTCGACTTCTTCCCAGATGATTTCTTAATCATGATTGACGAGAGCCACAT
GACTATGGGGCAAATCAAGGGAATGTACAATGGAGACCGCTCTCGTAAGGAAATGCTGGTTAATTATGGTTTCCGTTTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTTAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCTGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.547

100

0.995
  uvrB Streptococcus pneumoniae D39

99.547

100

0.995
  uvrB Streptococcus pneumoniae TIGR4

99.396

100

0.994