Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EQH28_RS05605 Genome accession   NZ_CP035252
Coordinates   1124317..1126305 (-) Length   662 a.a.
NCBI ID   WP_000607035.1    Uniprot ID   C1C7L7
Organism   Streptococcus pneumoniae strain TVO_1901934     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1119317..1131305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH28_RS05565 (EQH28_05910) coaB 1119617..1120306 (+) 690 WP_000699494.1 phosphopantothenate--cysteine ligase -
  EQH28_RS05570 (EQH28_05915) coaC 1120318..1120869 (+) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  EQH28_RS05575 (EQH28_05920) - 1120853..1121416 (+) 564 WP_000747408.1 ECF transporter S component -
  EQH28_RS05580 (EQH28_05925) - 1121698..1122225 (+) 528 WP_001097402.1 ECF transporter S component -
  EQH28_RS05585 (EQH28_05930) - 1122237..1122752 (+) 516 WP_000159176.1 transcription repressor NadR -
  EQH28_RS05590 (EQH28_05935) - 1122749..1123216 (-) 468 WP_000091537.1 8-oxo-dGTP diphosphatase -
  EQH28_RS05595 (EQH28_05940) - 1123289..1123777 (-) 489 WP_061751296.1 GNAT family N-acetyltransferase -
  EQH28_RS05600 (EQH28_05945) - 1123743..1124306 (-) 564 WP_000639832.1 GNAT family N-acetyltransferase -
  EQH28_RS05605 (EQH28_05950) uvrB 1124317..1126305 (-) 1989 WP_000607035.1 excinuclease ABC subunit UvrB Machinery gene
  EQH28_RS05610 (EQH28_05955) - 1126382..1127335 (-) 954 WP_000792099.1 CPBP family intramembrane glutamic endopeptidase -
  EQH28_RS05615 (EQH28_05960) - 1127508..1129673 (+) 2166 WP_000726260.1 ABC transporter substrate-binding protein/permease -
  EQH28_RS05620 (EQH28_05965) - 1129673..1130413 (+) 741 WP_001096339.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75737.77 Da        Isoelectric Point: 4.5848

>NTDB_id=296711 EQH28_RS05605 WP_000607035.1 1124317..1126305(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901934]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=296711 EQH28_RS05605 WP_000607035.1 1124317..1126305(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901934]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATCCGTGAGGTTGAGGCTCTGACAGGTCAGGTATTG
GGAGAGGTGGATCATTTGGCGATTTTCCCAGCTACTCACTTTGTGACCAATGACGACCATATGGAAGTTGCCGTTGCCAA
GATTCAAGCAGAATTAGAAGAGCAGTTAGCTGTCTTTGAGAAGGAAGGTAAATTGCTTGAAGCCCAGCGCTTGAAACAAC
GGACAGAGTACGATATCGAAATGCTGCGCGAGATGGGCTATACAAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTTCTCGACTTTTTCCCAGATGATTTTTTGATTATGATTGACGAGAGTCATAT
GACTATGGGACAAATAAAAGGCATGTACAATGGAGACCGTTCGCGTAAGGAAATGCTAGTAAATTATGGTTTCCGTTTAC
CGTCTGCCTTGGACAATCGTCCTCTCCGTCGTGAGGAGTTTGAAAGCCATGTGCATCAGATTGTTTACGTATCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACGGTGATTGAGCAAATCATTCGACCGACAGGGCTTTTGGATCCTGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGATCTCTTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACCACCTTGACCAAGAAAATGGCAGAGGACTTGACCGACTATTTCAAGGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGATCTCCGCTTGGGTGTCTTTGATGTCTTGGTTGGAAT
CAATCTCCTTCGTGAAGGGATTGACGTTCCTGAGGTTAGCTTGGTTGCCATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAGCGTGGACTCATCCAGACCATTGGGCGTGCCGCCCGTAACAGTGAAGGTCATGTCATCATGTATGCAGATACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1C7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.849

100

0.998
  uvrB Streptococcus pneumoniae D39

99.849

100

0.998
  uvrB Streptococcus pneumoniae TIGR4

99.698

100

0.997