Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SUB_RS02600 Genome accession   NC_012004
Coordinates   478624..479439 (+) Length   271 a.a.
NCBI ID   WP_170123120.1    Uniprot ID   -
Organism   Streptococcus uberis 0140J     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 473624..484439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS02575 (SUB0494) - 474461..474847 (+) 387 WP_012658025.1 hypothetical protein -
  SUB_RS02580 (SUB0495) - 474906..475697 (+) 792 WP_012658026.1 hypothetical protein -
  SUB_RS02590 (SUB0497) - 476300..476929 (+) 630 WP_012658028.1 ATP-binding cassette domain-containing protein -
  SUB_RS09805 - 476975..477114 (+) 140 Protein_477 DNA mismatch repair protein MutT -
  SUB_RS02595 (SUB0498) comE/blpR 477357..478097 (+) 741 WP_012658029.1 LytR/AlgR family response regulator transcription factor Regulator
  SUB_RS02600 (SUB0499) comD/blpH 478624..479439 (+) 816 WP_170123120.1 sensor histidine kinase Regulator
  SUB_RS09810 - 479449..479595 (-) 147 WP_080502297.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SUB_RS02605 (SUB0501) comA/nlmT 479631..481784 (-) 2154 WP_012658032.1 peptide cleavage/export ABC transporter Regulator
  SUB_RS02610 (SUB0502) - 482015..482248 (+) 234 Protein_482 ComC/BlpC family peptide pheromone/bacteriocin -
  SUB_RS02615 (SUB0505) - 482867..483091 (+) 225 WP_046388584.1 Blp family class II bacteriocin -
  SUB_RS02620 (SUB0506) - 483102..483302 (+) 201 WP_012658034.1 hypothetical protein -
  SUB_RS02630 (SUB0509) - 483979..484224 (+) 246 WP_012658036.1 garvicin Q family class II bacteriocin -

Sequence

Protein


Download         Length: 271 a.a.        Molecular weight: 32159.18 Da        Isoelectric Point: 5.4741

>NTDB_id=29655 SUB_RS02600 WP_170123120.1 478624..479439(+) (comD/blpH) [Streptococcus uberis 0140J]
MIQIISFFDYQLAIDTLFYRQLIVTLYFLLFLGILNSLDKQIREKLQKEIIFQKEIQFQNLENYSRHVEELYDQVRHFRH
DYANILSTLKIGIEEDDMTIVKDVFEKVLKDSNRELESHKYDITRLVNIEDRALKSLLASKFIRMEEKGITVSLEIPYKI
TICEMELIDFITIVSIFIDNAIEETFLSKNPKITFAFFEDSNRQICIIENSTRNNQIDITNIFNEFETSKGKGRGIGLYK
VSRILKKYHSVNLKTQSLDYKFTQILEIIFE

Nucleotide


Download         Length: 816 bp        

>NTDB_id=29655 SUB_RS02600 WP_170123120.1 478624..479439(+) (comD/blpH) [Streptococcus uberis 0140J]
ATGATTCAGATCATTTCATTTTTTGATTATCAATTAGCAATTGATACTCTATTTTATCGTCAACTTATTGTAACTTTATA
TTTTTTATTATTTTTAGGTATTTTGAATTCTTTGGACAAGCAAATTAGAGAGAAGCTTCAAAAAGAAATTATTTTTCAAA
AAGAAATTCAATTTCAAAACCTTGAAAATTACAGTCGACATGTTGAAGAGTTGTATGATCAGGTACGACATTTTAGACAC
GATTATGCTAATATCTTATCAACATTAAAGATTGGAATTGAAGAAGATGATATGACTATTGTAAAGGATGTATTTGAAAA
AGTTTTAAAGGATTCAAATAGAGAATTGGAAAGTCATAAGTATGATATTACACGATTAGTGAATATCGAAGACAGAGCTC
TGAAGAGTTTATTGGCTTCTAAATTTATCCGAATGGAAGAAAAAGGAATAACTGTTTCTCTAGAAATTCCTTATAAAATA
ACAATTTGTGAGATGGAATTGATAGATTTTATAACGATTGTATCAATATTTATTGATAATGCAATTGAGGAAACATTTTT
ATCAAAGAACCCTAAGATAACATTTGCATTTTTTGAGGATAGTAATAGACAAATCTGTATCATTGAAAATAGTACTCGAA
ATAATCAAATTGATATAACAAATATCTTTAATGAATTTGAAACTTCTAAAGGTAAGGGCAGAGGCATTGGACTTTATAAG
GTATCAAGAATATTAAAAAAATATCATTCTGTAAATTTAAAGACCCAAAGCCTAGACTATAAATTTACACAAATATTAGA
AATTATTTTTGAATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(165-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

41.045

98.893

0.406
  comD/comD3 Streptococcus equinus JB1

39.6

92.251

0.365

Multiple sequence alignment