Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EQH37_RS05865 Genome accession   NZ_CP035243
Coordinates   1177973..1179961 (-) Length   662 a.a.
NCBI ID   WP_000607032.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1172973..1184961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS05825 (EQH37_06155) coaB 1173273..1173962 (+) 690 WP_000699503.1 phosphopantothenate--cysteine ligase -
  EQH37_RS05830 (EQH37_06160) coaC 1173974..1174525 (+) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  EQH37_RS05835 (EQH37_06165) - 1174509..1175072 (+) 564 WP_000747408.1 ECF transporter S component -
  EQH37_RS05840 (EQH37_06170) - 1175354..1175881 (+) 528 WP_001097402.1 ECF transporter S component -
  EQH37_RS05845 (EQH37_06175) - 1175893..1176408 (+) 516 WP_000159168.1 transcription repressor NadR -
  EQH37_RS05850 (EQH37_06180) - 1176405..1176872 (-) 468 WP_000091534.1 8-oxo-dGTP diphosphatase -
  EQH37_RS05855 (EQH37_06185) - 1176946..1177434 (-) 489 WP_000216005.1 GNAT family N-acetyltransferase -
  EQH37_RS05860 (EQH37_06190) - 1177400..1177963 (-) 564 WP_000639842.1 GNAT family N-acetyltransferase -
  EQH37_RS05865 (EQH37_06195) uvrB 1177973..1179961 (-) 1989 WP_000607032.1 excinuclease ABC subunit UvrB Machinery gene
  EQH37_RS05870 (EQH37_06200) - 1180038..1180991 (-) 954 WP_000792125.1 CPBP family intramembrane glutamic endopeptidase -
  EQH37_RS05875 (EQH37_06205) - 1181164..1183329 (+) 2166 WP_054366180.1 ABC transporter substrate-binding protein/permease -
  EQH37_RS05880 (EQH37_06210) - 1183329..1184069 (+) 741 WP_001096316.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75723.74 Da        Isoelectric Point: 4.5833

>NTDB_id=295759 EQH37_RS05865 WP_000607032.1 1177973..1179961(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901946]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDVNSLNKQERKDLVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=295759 EQH37_RS05865 WP_000607032.1 1177973..1179961(-) (uvrB) [Streptococcus pneumoniae strain TVO_1901946]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCACAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGCAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAACGGGGTTGAGAACTATTCACGACACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTCTTAGATTTCTTCCCAGATGATTTTTTAATTATGATTGACGAGAGTCACAT
GACCATGGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAGGAAATGCTAGTAAATTATGGTTTCCGTTTAC
CGTCTGCCTTGGACAATCGTCCTCTCCGTCGTGAGGAGTTTGAAAGCCATGTGCATCAGATTGTTTACGTATCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACGGTGATTGAGCAAATCATTCGACCGACAGGGCTTTTGGATCCTGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGATCTCTTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACCACCTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTTAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAACATGG
TATCGTTCCACAAACCATTAAGAAAGAAATCCGTGACCTGATTGCCGTAACTAAGGCAGTTGCTAAGGAAGAAGACAAGG
AAGTTGATGTTAATAGCCTCAACAAACAAGAACGTAAAGATCTTGTTAAGAAACTCGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTAGCAGCACAGATTCGTGATATGATGTTGGAAGTCAAGGCGTTGGATTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

UvrB/uvrC motif (UVR)

(627-660)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.698

100

0.997
  uvrB Streptococcus pneumoniae D39

99.698

100

0.997
  uvrB Streptococcus pneumoniae TIGR4

99.547

100

0.995

Multiple sequence alignment