Detailed information NTG0295559

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: DCS61_RS20610
• Genome accession: NZ_CP029707
• Coordinates: 4246823..4248160 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain K34-7
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 4241823..4253160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DCS61_RS20585 (DCS61_20585)	pgeF	4241966..4242694 (-)	729	WP_003161770.1	peptidoglycan editing factor PgeF	-
DCS61_RS20590 (DCS61_20590)	rluD	4242691..4243653 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
DCS61_RS20595 (DCS61_20595)	-	4243799..4244824 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
DCS61_RS20600 (DCS61_20600)	-	4244981..4245226 (+)	246	WP_003102591.1	PP0621 family protein	-
DCS61_RS20605 (DCS61_20605)	pilS	4245216..4246808 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator
DCS61_RS20610 (DCS61_20610)	pilR	4246823..4248160 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
DCS61_RS20615 (DCS61_20615)	thiO	4248206..4249300 (-)	1095	WP_023084775.1	glycine oxidase ThiO	-
DCS61_RS20620 (DCS61_20620)	-	4249435..4249944 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
DCS61_RS20625 (DCS61_20625)	-	4250050..4250556 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
DCS61_RS20630 (DCS61_20630)	pilV	4250547..4251104 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
DCS61_RS20635 (DCS61_20635)	pilW	4251101..4251925 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
DCS61_RS20640 (DCS61_20640)	pilX	4251922..4252509 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=295559 DCS61_RS20610 WP_003094694.1 4246823..4248160(+) (pilR) [Pseudomonas aeruginosa strain K34-7]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=295559 DCS61_RS20610 WP_003094694.1 4246823..4248160(+) (pilR) [Pseudomonas aeruginosa strain K34-7]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384