Detailed information NTG0295439

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DMC40_RS07750
• Genome accession: NZ_CP029694
• Coordinates: 1467442..1468443 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain ABC020055975
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1462442..1473443

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DMC40_RS07735 (DMC40_07735)	thrS	1462612..1464555 (-)	1944	WP_011054265.1	threonine--tRNA ligase	-
DMC40_RS07740 (DMC40_07740)	-	1464977..1466311 (-)	1335	WP_002985676.1	glycosyltransferase family 4 protein	-
DMC40_RS07745 (DMC40_07745)	-	1466313..1467311 (-)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DMC40_RS07750 (DMC40_07750)	ccpA	1467442..1468443 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DMC40_RS07755 (DMC40_07755)	-	1468617..1469702 (+)	1086	WP_011054264.1	Xaa-Pro peptidase family protein	-
DMC40_RS07760 (DMC40_07760)	-	1469751..1470416 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DMC40_RS07765 (DMC40_07765)	-	1470427..1470804 (+)	378	WP_002985686.1	VOC family protein	-
DMC40_RS07770 (DMC40_07770)	-	1470949..1471875 (+)	927	WP_011106859.1	glycosyltransferase family 2 protein	-
DMC40_RS07775 (DMC40_07775)	-	1472086..1472769 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=295439 DMC40_RS07750 WP_002985680.1 1467442..1468443(-) (ccpA) [Streptococcus pyogenes strain ABC020055975]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=295439 DMC40_RS07750 WP_002985680.1 1467442..1468443(-) (ccpA) [Streptococcus pyogenes strain ABC020055975]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCACGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559