Detailed information NTG0295437

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EQH41_RS09435
• Genome accession: NZ_CP035239
• Coordinates: 1885664..1886563 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904858.1
• Uniprot ID: A0A0H2URY1
• Organism: Streptococcus pneumoniae strain TVO_TIGR4
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1880664..1891563

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH41_RS09415 (EQH41_10035)	rsmA	1881418..1882290 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
EQH41_RS09420 (EQH41_10040)	-	1882421..1882729 (-)	309	WP_000333257.1	hypothetical protein	-
EQH41_RS09425 (EQH41_10045)	-	1882722..1883363 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
EQH41_RS09430 (EQH41_10050)	-	1883365..1885395 (-)	2031	WP_000825267.1	bacteriocin-associated integral membrane family protein	-
EQH41_RS09435 (EQH41_10055)	comR	1885664..1886563 (-)	900	WP_000904858.1	helix-turn-helix transcriptional regulator	Regulator
EQH41_RS09440 (EQH41_10060)	rnmV	1886635..1887195 (-)	561	WP_000660004.1	ribonuclease M5	-
EQH41_RS09445 (EQH41_10065)	-	1887195..1887968 (-)	774	WP_000575607.1	TatD family hydrolase	-
EQH41_RS09450 (EQH41_10075)	-	1888273..1889244 (-)	972	Protein_1880	DUF1542 domain-containing protein	-
EQH41_RS09455 (EQH41_10080)	rpmH	1889450..1889584 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
EQH41_RS09460 (EQH41_10085)	-	1889729..1890943 (-)	1215	WP_000666479.1	pyridoxal phosphate-dependent aminotransferase	-
EQH41_RS09465 (EQH41_10090)	-	1891099..1891393 (-)	295	Protein_1883	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.11 Da
• Isoelectric Point: 4.7119

>NTDB_id=295437 EQH41_RS09435 WP_000904858.1 1885664..1886563(-) (comR) [Streptococcus pneumoniae strain TVO_TIGR4]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=295437 EQH41_RS09435 WP_000904858.1 1885664..1886563(-) (comR) [Streptococcus pneumoniae strain TVO_TIGR4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

3D structure

• AlphaFold DB: A0A0H2URY1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361