Detailed information NTG0295280

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EQH42_RS05550
• Genome accession: NZ_CP035238
• Coordinates: 1124450..1126438 (-)
• Length: 662 a.a.
• NCBI ID: WP_000607031.1
• Uniprot ID: Q8DPK7
• Organism: Streptococcus pneumoniae strain TVO_D39
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1119450..1131438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH42_RS05510 (EQH42_05825)	coaB	1119750..1120439 (+)	690	WP_000699498.1	phosphopantothenate--cysteine ligase	-
EQH42_RS05515 (EQH42_05830)	coaC	1120451..1121002 (+)	552	WP_001284128.1	phosphopantothenoylcysteine decarboxylase	-
EQH42_RS05520 (EQH42_05835)	-	1120986..1121549 (+)	564	WP_000747408.1	ECF transporter S component	-
EQH42_RS05525 (EQH42_05840)	-	1121831..1122358 (+)	528	WP_001097402.1	ECF transporter S component	-
EQH42_RS05530 (EQH42_05845)	-	1122370..1122885 (+)	516	WP_000159176.1	transcription repressor NadR	-
EQH42_RS05535 (EQH42_05850)	-	1122882..1123349 (-)	468	WP_000091534.1	8-oxo-dGTP diphosphatase	-
EQH42_RS05540 (EQH42_05855)	-	1123423..1123911 (-)	489	WP_000216018.1	GNAT family N-acetyltransferase	-
EQH42_RS05545 (EQH42_05860)	-	1123877..1124440 (-)	564	WP_000639832.1	GNAT family N-acetyltransferase	-
EQH42_RS05550 (EQH42_05865)	uvrB	1124450..1126438 (-)	1989	WP_000607031.1	excinuclease ABC subunit UvrB	Machinery gene
EQH42_RS05555 (EQH42_05870)	-	1126515..1127468 (-)	954	WP_000792121.1	CPBP family intramembrane glutamic endopeptidase	-
EQH42_RS05560 (EQH42_05875)	-	1127641..1129806 (+)	2166	WP_000726272.1	ABC transporter substrate-binding protein/permease	-
EQH42_RS05565 (EQH42_05880)	-	1129806..1130546 (+)	741	WP_001096316.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75751.80 Da
• Isoelectric Point: 4.5848

>NTDB_id=295280 EQH42_RS05550 WP_000607031.1 1124450..1126438(-) (uvrB) [Streptococcus pneumoniae strain TVO_D39]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide

• Length: 1989 bp

>NTDB_id=295280 EQH42_RS05550 WP_000607031.1 1124450..1126438(-) (uvrB) [Streptococcus pneumoniae strain TVO_D39]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATCCGTGAGGTTGAGGCTCTGACAGGTCAGGTATTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGCTGCGCGAGATGGGCTATACAAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGTAGTGAAGGTGAGCCTCCTTATACGCTTCTCGACTTTTTCCCAGATGATTTTTTGATTATGATTGACGAGAGTCATAT
GACTATGGGACAAATAAAAGGCATGTACAATGGAGACCGTTCGCGTAAGGAAATGCTAGTAAATTATGGTTTCCGTTTAC
CGTCTGCCTTGGACAATCGTCCTCTCCGTCGTGAGGAGTTTGAAAGCCATGTGCATCAGATTGTTTACGTATCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACGGTGATTGAGCAAATCATTCGACCGACAGGGCTTTTGGATCCTGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGATCTCTTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACCACCTTGACCAAGAAAATGGCAGAGGACTTGACCGACTATTTCAAGGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGATCTCCGCTTGGGTGTCTTTGATGTCTTGGTTGGAAT
CAATCTCCTTCGTGAAGGGATTGACGTTCCTGAGGTTAGCTTGGTTGCCATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAGCGTGGACTCATCCAGACCATTGGGCGTGCCGCCCGTAACAGTGAAGGTCATGTCATCATGTATGCAGATACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB/uvrC motif (UVR) (626-660)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: Q8DPK7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	100	100	1
uvrB	Streptococcus pneumoniae D39	100	100	1
uvrB	Streptococcus pneumoniae TIGR4	99.849	100	0.998