Detailed information NTG0029513

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPN23F_RS10250
• Genome accession: NC_011900
• Coordinates: 1950922..1951821 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904834.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae ATCC 700669
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1945922..1956821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN23F_RS10225 (SPN23F20050)	rsmA	1946252..1947124 (-)	873	WP_001216856.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SPN23F_RS10230 (SPN23F20060)	-	1947255..1947563 (-)	309	WP_000333253.1	hypothetical protein	-
SPN23F_RS10235 (SPN23F20070)	-	1947556..1948197 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
SPN23F_RS10240 (SPN23F20080)	-	1948199..1950229 (-)	2031	WP_000825254.1	bacteriocin-associated integral membrane family protein	-
SPN23F_RS10245 (SPN23F20090)	-	1950306..1950602 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
SPN23F_RS10250 (SPN23F20100)	comR	1950922..1951821 (-)	900	WP_000904834.1	helix-turn-helix transcriptional regulator	Regulator
SPN23F_RS10255 (SPN23F20110)	rnmV	1951893..1952453 (-)	561	WP_000660009.1	ribonuclease M5	-
SPN23F_RS10260 (SPN23F20120)	-	1952453..1953226 (-)	774	WP_000575597.1	TatD family hydrolase	-
SPN23F_RS10265 (SPN23F20130)	-	1953531..1954502 (-)	972	Protein_1952	DUF1542 domain-containing protein	-
SPN23F_RS10270 (SPN23F20140)	rpmH	1954708..1954842 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
SPN23F_RS10275 (SPN23F20150)	-	1954987..1956201 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPN23F_RS10280 (SPN23F20160)	-	1956357..1956650 (-)	294	WP_000977368.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35263.10 Da
• Isoelectric Point: 4.9762

>NTDB_id=29513 SPN23F_RS10250 WP_000904834.1 1950922..1951821(-) (comR) [Streptococcus pneumoniae ATCC 700669]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=29513 SPN23F_RS10250 WP_000904834.1 1950922..1951821(-) (comR) [Streptococcus pneumoniae ATCC 700669]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	38.144	97.324	0.371
comR	Streptococcus suis 05ZYH33	38.144	97.324	0.371
comR	Streptococcus suis D9	36.12	100	0.361