Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   EQH44_RS05760 Genome accession   NZ_CP035236
Coordinates   1155520..1157508 (-) Length   662 a.a.
NCBI ID   WP_000607035.1    Uniprot ID   C1C7L7
Organism   Streptococcus pneumoniae strain TVO_1902282     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1150520..1162508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH44_RS05720 (EQH44_06055) coaB 1150820..1151509 (+) 690 WP_000699495.1 phosphopantothenate--cysteine ligase -
  EQH44_RS05725 (EQH44_06060) coaC 1151521..1152072 (+) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  EQH44_RS05730 (EQH44_06065) - 1152056..1152619 (+) 564 WP_000747408.1 ECF transporter S component -
  EQH44_RS05735 (EQH44_06070) - 1152901..1153428 (+) 528 WP_001097402.1 ECF transporter S component -
  EQH44_RS05740 (EQH44_06075) - 1153440..1153955 (+) 516 WP_000159171.1 transcription repressor NadR -
  EQH44_RS05745 (EQH44_06080) - 1153952..1154419 (-) 468 WP_000091534.1 8-oxo-dGTP diphosphatase -
  EQH44_RS05750 (EQH44_06085) - 1154493..1154981 (-) 489 WP_000216018.1 GNAT family N-acetyltransferase -
  EQH44_RS05755 (EQH44_06090) - 1154947..1155510 (-) 564 WP_000639831.1 GNAT family N-acetyltransferase -
  EQH44_RS05760 (EQH44_06095) uvrB 1155520..1157508 (-) 1989 WP_000607035.1 excinuclease ABC subunit UvrB Machinery gene
  EQH44_RS05765 (EQH44_06100) - 1157585..1158538 (-) 954 WP_000792116.1 CPBP family intramembrane glutamic endopeptidase -
  EQH44_RS05770 (EQH44_06105) - 1158708..1160873 (+) 2166 WP_000726272.1 ABC transporter substrate-binding protein/permease -
  EQH44_RS05775 (EQH44_06110) - 1160873..1161613 (+) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75737.77 Da        Isoelectric Point: 4.5848

>NTDB_id=295049 EQH44_RS05760 WP_000607035.1 1155520..1157508(-) (uvrB) [Streptococcus pneumoniae strain TVO_1902282]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=295049 EQH44_RS05760 WP_000607035.1 1155520..1157508(-) (uvrB) [Streptococcus pneumoniae strain TVO_1902282]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATCCGTGAGGTTGAGGCTCTGACAGGTCAGGTATTG
GGAGAGGTGGATCATTTGGCGATTTTCCCAGCTACTCACTTTGTGACCAATGACGACCATATGGAAGTTGCCGTTGCCAA
GATTCAAGCAGAATTAGAAGAGCAGTTAGCTGTCTTTGAGAAGGAAGGTAAATTGCTTGAAGCCCAGCGCTTGAAACAAC
GGACAGAGTACGATATCGAAATGCTGCGCGAGATGGGCTATACAAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGTAGTGAAGGTGAGCCTCCTTATACGCTTCTCGACTTTTTCCCAGATGATTTTTTGATTATGATTGACGAGAGTCATAT
GACTATGGGACAAATAAAAGGCATGTACAATGGAGACCGTTCGCGTAAGGAAATGCTAGTAAATTATGGTTTCCGTTTAC
CGTCTGCCTTGGACAATCGTCCTCTCCGTCGTGAGGAGTTTGAAAGCCATGTGCATCAGATTGTTTACGTATCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACGGTGATTGAGCAAATCATTCGACCGACAGGGCTTTTGGATCCTGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGATCTCTTAGGTGAAATCAATGCCCGTGTTGAAAAGAATGAACGAACCT
TTATCACCACCTTGACCAAGAAAATGGCAGAGGACTTGACCGACTATTTCAAGGAAATGGGCATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGATCTCCGCTTGGGTGTCTTTGATGTCTTGGTTGGAAT
CAATCTCCTTCGTGAAGGGATTGACGTTCCTGAGGTTAGCTTGGTTGCCATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GTAACGAGCGTGGACTCATCCAGACCATTGGGCGTGCCGCCCGTAACAGTGAAGGTCATGTCATCATGTATGCAGATACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(626-660)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1C7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.849

100

0.998
  uvrB Streptococcus pneumoniae D39

99.849

100

0.998
  uvrB Streptococcus pneumoniae TIGR4

99.698

100

0.997

Multiple sequence alignment