Detailed information NTG0294813

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: EQH46_RS05875
• Genome accession: NZ_CP035234
• Coordinates: 1171890..1173878 (-)
• Length: 662 a.a.
• NCBI ID: WP_000607027.1
• Uniprot ID: Q54986
• Organism: Streptococcus pneumoniae strain TVO_1902277
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1166890..1178878

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH46_RS05835 (EQH46_06135)	coaB	1167190..1167879 (+)	690	WP_000699488.1	phosphopantothenate--cysteine ligase	-
EQH46_RS05840 (EQH46_06140)	coaC	1167891..1168442 (+)	552	WP_001284129.1	phosphopantothenoylcysteine decarboxylase	-
EQH46_RS05845 (EQH46_06145)	-	1168426..1168989 (+)	564	WP_000747408.1	ECF transporter S component	-
EQH46_RS05850 (EQH46_06150)	-	1169271..1169798 (+)	528	WP_001097402.1	ECF transporter S component	-
EQH46_RS05855 (EQH46_06155)	-	1169810..1170325 (+)	516	WP_000159181.1	transcription repressor NadR	-
EQH46_RS05860 (EQH46_06160)	-	1170322..1170789 (-)	468	WP_000091530.1	8-oxo-dGTP diphosphatase	-
EQH46_RS05865 (EQH46_06165)	-	1170842..1171351 (-)	510	WP_000216011.1	GNAT family N-acetyltransferase	-
EQH46_RS05870 (EQH46_06170)	-	1171317..1171880 (-)	564	WP_000639843.1	GNAT family N-acetyltransferase	-
EQH46_RS05875 (EQH46_06175)	uvrB	1171890..1173878 (-)	1989	WP_000607027.1	excinuclease ABC subunit UvrB	Machinery gene
EQH46_RS05880 (EQH46_06180)	-	1173955..1174908 (-)	954	WP_000792099.1	CPBP family intramembrane glutamic endopeptidase	-
EQH46_RS05885 (EQH46_06185)	-	1175081..1177246 (+)	2166	WP_000726258.1	ABC transporter substrate-binding protein/permease	-
EQH46_RS05890 (EQH46_06190)	-	1177246..1177986 (+)	741	WP_001096313.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 662 a.a.
• Molecular weight: 75733.76 Da
• Isoelectric Point: 4.5848

>NTDB_id=294813 EQH46_RS05875 WP_000607027.1 1171890..1173878(-) (uvrB) [Streptococcus pneumoniae strain TVO_1902277]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKALD

Nucleotide

• Length: 1989 bp

>NTDB_id=294813 EQH46_RS05875 WP_000607027.1 1171890..1173878(-) (uvrB) [Streptococcus pneumoniae strain TVO_1902277]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGCAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAAAATTATTCTCGCCACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTTCTCGACTTCTTCCCAGATGATTTCTTGATTATGATTGACGAGAGTCATAT
GACCATAGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTGGTTAATTATGGTTTCCGTTTGC
CGTCTGCTTTGGACAATCGTCCTCTACGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACCGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCAGAGGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGACAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGGCCTATAATGAAGAGCATGG
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAAGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATCCGTGATATGATGTTGGAAGTCAAGGCCTTGGATTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB/uvrC motif (UVR) (626-660)

• Helicase conserved C-terminal domain (Helicase_C) (443-549)

• Type III restriction enzyme, res subunit (ResIII) (17-143)

• UvrB interaction domain (UvrB_inter) (164-254)

3D structure

• AlphaFold DB: Q54986

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae TIGR4	100	100	1
uvrB	Streptococcus pneumoniae R6	99.849	100	0.998
uvrB	Streptococcus pneumoniae D39	99.849	100	0.998