Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CSC52_RS13190 Genome accession   NZ_CP029658
Coordinates   2472422..2472991 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain AR_0467     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2467422..2477991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC52_RS13145 (CSC52_2473) - 2467897..2468505 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  CSC52_RS13150 (CSC52_2474) rplL 2468680..2469048 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CSC52_RS13155 (CSC52_2475) rplJ 2469091..2469591 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  CSC52_RS13165 (CSC52_2476) rplA 2469862..2470554 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  CSC52_RS13170 (CSC52_2477) rplK 2470762..2471184 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  CSC52_RS13175 (CSC52_2478) nusG 2471365..2471913 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  CSC52_RS13180 (CSC52_2479) secE 2471926..2472108 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CSC52_RS13185 (CSC52_2480) rpmG 2472164..2472307 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  CSC52_RS13190 (CSC52_2481) sigH 2472422..2472991 (-) 570 WP_000872882.1 RNA polymerase sigma factor Regulator
  CSC52_RS13195 (CSC52_2482) - 2473072..2473596 (-) 525 WP_000664737.1 NYN domain-containing protein -
  CSC52_RS13200 (CSC52_2483) rlmB 2473596..2474342 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CSC52_RS13205 (CSC52_2484) - 2474350..2474754 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CSC52_RS13210 (CSC52_2485) cysS 2474747..2476147 (-) 1401 WP_000631969.1 cysteine--tRNA ligase -
  CSC52_RS13215 (CSC52_2486) cysE 2476131..2476778 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=294740 CSC52_RS13190 WP_000872882.1 2472422..2472991(-) (sigH) [Staphylococcus aureus strain AR_0467]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=294740 CSC52_RS13190 WP_000872882.1 2472422..2472991(-) (sigH) [Staphylococcus aureus strain AR_0467]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment