Detailed information NTG0294705

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC52_RS01115
• Genome accession: NZ_CP029658
• Coordinates: 240017..240904 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AR_0467
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 235017..245904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC52_RS01085 (CSC52_0209)	-	235749..236510 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
CSC52_RS01090 (CSC52_0210)	-	236755..237210 (+)	456	WP_110184134.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC52_RS15830	-	237332..237433 (+)	102	WP_000731976.1	SE2200 family small protein	-
CSC52_RS01100 (CSC52_0211)	-	237493..238917 (-)	1425	WP_000953755.1	alkaline phosphatase	-
CSC52_RS01105 (CSC52_0212)	-	239115..239315 (+)	201	WP_000604730.1	hypothetical protein	-
CSC52_RS01110 (CSC52_0213)	braR	239341..240006 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC52_RS01115 (CSC52_0214)	braS	240017..240904 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC52_RS01120 (CSC52_0215)	-	241012..241767 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC52_RS01125 (CSC52_0216)	-	241764..243764 (+)	2001	WP_110184135.1	ABC transporter permease	-
CSC52_RS01130	-	244423..244536 (+)	114	Protein_209	hypothetical protein	-
CSC52_RS01140	-	244918..245178 (+)	261	WP_001791974.1	hypothetical protein	-
CSC52_RS01145 (CSC52_0218)	-	245188..245685 (+)	498	WP_001065268.1	glutathione peroxidase	-
CSC52_RS01150	-	245793..245885 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=294705 CSC52_RS01115 WP_000143425.1 240017..240904(+) (braS) [Staphylococcus aureus strain AR_0467]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=294705 CSC52_RS01115 WP_000143425.1 240017..240904(+) (braS) [Staphylococcus aureus strain AR_0467]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACCAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1