Detailed information NTG0294366

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DLJ55_RS10635
• Genome accession: NZ_CP029627
• Coordinates: 2033024..2034067 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain MOK042
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2028024..2039067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DLJ55_RS10605 (DLJ55_10605)	-	2028446..2029702 (-)	1257	WP_001793428.1	aminopeptidase	-
DLJ55_RS10610 (DLJ55_10610)	-	2029705..2029905 (-)	201	WP_000180463.1	DUF1128 family protein	-
DLJ55_RS10615 (DLJ55_10615)	-	2030052..2030516 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DLJ55_RS10620 (DLJ55_10620)	-	2030523..2030798 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DLJ55_RS10625 (DLJ55_10625)	-	2031076..2032293 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
DLJ55_RS10630 (DLJ55_10630)	vraR	2032405..2033034 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DLJ55_RS10635 (DLJ55_10635)	vraS	2033024..2034067 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DLJ55_RS10640 (DLJ55_10640)	liaF	2034064..2034765 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DLJ55_RS10645 (DLJ55_10645)	-	2034780..2035166 (-)	387	WP_001110179.1	hypothetical protein	-
DLJ55_RS10650 (DLJ55_10650)	map	2035383..2036141 (-)	759	WP_110166374.1	type I methionyl aminopeptidase	-
DLJ55_RS10655 (DLJ55_10655)	-	2036557..2037543 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
DLJ55_RS10665 (DLJ55_10665)	-	2037974..2038387 (-)	414	WP_001549145.1	hypothetical protein	-
DLJ55_RS10670 (DLJ55_10670)	-	2038416..2038526 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294366 DLJ55_RS10635 WP_001017131.1 2033024..2034067(-) (vraS) [Staphylococcus aureus strain MOK042]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294366 DLJ55_RS10635 WP_001017131.1 2033024..2034067(-) (vraS) [Staphylococcus aureus strain MOK042]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1