Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EQW70_RS09535 Genome accession   NZ_CP035226
Coordinates   1804808..1806691 (+) Length   627 a.a.
NCBI ID   WP_128740335.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM103517     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1799808..1811691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQW70_RS09520 (EQW70_09520) ymcA 1800845..1801276 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  EQW70_RS09525 (EQW70_09525) cotE 1801538..1802083 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  EQW70_RS09530 (EQW70_09530) hexA 1802216..1804792 (+) 2577 WP_070548989.1 DNA mismatch repair protein MutS Machinery gene
  EQW70_RS09535 (EQW70_09535) hexB 1804808..1806691 (+) 1884 WP_128740335.1 DNA mismatch repair endonuclease MutL Machinery gene
  EQW70_RS09540 (EQW70_09540) ymzD 1807089..1807544 (-) 456 WP_080121135.1 regulatory YrvL family protein -
  EQW70_RS09545 (EQW70_09545) - 1807699..1808256 (-) 558 WP_014479830.1 hypothetical protein -
  EQW70_RS09550 (EQW70_09550) pksA 1808377..1808994 (+) 618 WP_038828274.1 TetR/AcrR family transcriptional regulator -
  EQW70_RS09555 (EQW70_09555) pksB 1809184..1809861 (+) 678 WP_015715908.1 MBL fold metallo-hydrolase -
  EQW70_RS09560 (EQW70_09560) - 1809972..1810238 (+) 267 WP_120363368.1 hypothetical protein -
  EQW70_RS09565 (EQW70_09565) fabD 1810235..1811101 (+) 867 WP_128740336.1 ACP S-malonyltransferase -
  EQW70_RS22170 - 1811421..1811576 (-) 156 WP_164914261.1 hypothetical protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70595.50 Da        Isoelectric Point: 5.6795

>NTDB_id=294234 EQW70_RS09535 WP_128740335.1 1804808..1806691(+) (hexB) [Bacillus subtilis strain SRCM103517]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKHQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPEKKVPEKSTASSYSPMKLSSVVKEPFDAEEELPPLQFDAPPI
VDQEQTLEVSDVSEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=294234 EQW70_RS09535 WP_128740335.1 1804808..1806691(+) (hexB) [Bacillus subtilis strain SRCM103517]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCTCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCAAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGCGACGGA
ATTAAAGATGTATTTAAACACCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTAATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGTCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGTTTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAAGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTCGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATACACC
ATTCCACTTATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.497

100

0.467