Detailed information NTG0294233

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: EQW70_RS09530
• Genome accession: NZ_CP035226
• Coordinates: 1802216..1804792 (+)
• Length: 858 a.a.
• NCBI ID: WP_070548989.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM103517
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1797216..1809792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQW70_RS09510 (EQW70_09510)	kbl	1797988..1799166 (+)	1179	WP_128740334.1	glycine C-acetyltransferase	-
EQW70_RS09515 (EQW70_09515)	miaB	1799314..1800843 (+)	1530	WP_014664026.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
EQW70_RS09520 (EQW70_09520)	ymcA	1800845..1801276 (+)	432	WP_003231834.1	regulatory iron-sulfur-containing complex subunit RicA	Regulator
EQW70_RS09525 (EQW70_09525)	cotE	1801538..1802083 (+)	546	WP_003231833.1	outer spore coat protein CotE	-
EQW70_RS09530 (EQW70_09530)	hexA	1802216..1804792 (+)	2577	WP_070548989.1	DNA mismatch repair protein MutS	Machinery gene
EQW70_RS09535 (EQW70_09535)	hexB	1804808..1806691 (+)	1884	WP_128740335.1	DNA mismatch repair endonuclease MutL	Machinery gene
EQW70_RS09540 (EQW70_09540)	ymzD	1807089..1807544 (-)	456	WP_080121135.1	regulatory YrvL family protein	-
EQW70_RS09545 (EQW70_09545)	-	1807699..1808256 (-)	558	WP_014479830.1	hypothetical protein	-
EQW70_RS09550 (EQW70_09550)	pksA	1808377..1808994 (+)	618	WP_038828274.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97619.84 Da
• Isoelectric Point: 5.3551

>NTDB_id=294233 EQW70_RS09530 WP_070548989.1 1802216..1804792(+) (hexA) [Bacillus subtilis strain SRCM103517]
MAGYTPMIQQYLKIKAEHQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGAAEKIPMCGVPYHSASAYIEQLIKK
GYKVAICEQTEDPKAAKGVVKREVVQLITPGTVMDGKGIHESENNFIASVSACSNGYGLALSDLTTGENLAVLIERLEDV
ISEIYSVGAREIVVSGSLDADTVAQLRERCGATISIEDGETDEHVTIIEHLNNEDITKTFMRLYTYLKRTQKRSLDHLQP
LQVYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRVNQIEERQEMVETLMSHFF
EREDLRERLKEVYDLERLAGRVAFGNVNARDLIQLKESLKQVPGIKQLVASLAHDKAKERAKRIDPCGDVLKLLEEALYE
NPPLSVKEGNLIKDGYNQKLDEYRDASRNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANLHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFTELREKVKQYIPRLQLLAKQMSELDALQCFATISENRHYTKPEF
SKDEVEVIEGRHPVVEKVMDSQEYVPNNCMMGDNRQMLLITGPNMSGKSTYMRQIALISIMAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVNATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHDHIGAKTLFSTHYHEL
TVLEDKLPQLKNVHVRAEEYNGTVVFLHQIKEGAADKSYGIHVAQLAELPGDLIARAQDILKELEHSGNKPEVPVQKPQV
KEEPAQLSFFDEAEKPAETPKLSKKEKQVIDAFKSLNILDMTPLEAMNEMYKLQKKLH

Nucleotide

• Length: 2577 bp

>NTDB_id=294233 EQW70_RS09530 WP_070548989.1 1802216..1804792(+) (hexA) [Bacillus subtilis strain SRCM103517]
ATGGCCGGTTATACGCCTATGATACAGCAATATTTAAAAATAAAGGCAGAGCACCAGGATGCCTTTTTATTTTTTCGCCT
GGGTGATTTTTATGAAATGTTTTTTGAGGACGCCAAAAAAGCGTCACAAGAGCTGGAAATTACGTTAACGAGCAGAGATG
GCGGTGCGGCTGAAAAAATACCGATGTGCGGTGTGCCGTATCATTCTGCTTCCGCGTATATCGAACAGCTTATTAAAAAA
GGATACAAAGTGGCGATCTGTGAACAGACGGAAGATCCGAAAGCCGCAAAGGGCGTTGTGAAAAGAGAAGTGGTTCAGCT
GATTACGCCCGGAACTGTAATGGACGGCAAAGGCATCCATGAATCGGAAAATAACTTTATCGCATCTGTTTCAGCCTGCT
CGAACGGATACGGACTTGCGCTGTCTGATTTAACAACGGGAGAAAATTTGGCTGTTTTGATTGAACGGCTTGAAGACGTC
ATATCAGAAATTTATTCAGTCGGCGCACGGGAAATCGTGGTTTCAGGAAGCTTGGATGCCGATACAGTGGCACAGCTGAG
AGAGCGGTGCGGTGCAACGATTTCAATTGAAGACGGAGAAACAGACGAACACGTAACGATCATTGAGCACTTAAATAATG
AAGATATAACAAAAACATTTATGCGCTTATATACGTATCTGAAAAGAACCCAAAAGCGCAGCCTTGATCATCTTCAGCCC
TTGCAGGTGTATGAGCTTGAGGAAGCGATGAAAATTGACTTGTACTCAAAGCGTAATCTGGAGCTGACCGAAACAATCCG
TTCAAAAAATAAAAAAGGCTCCCTTTTGTGGCTGCTGGATGAAACAAAAACGGCAATGGGAGGCCGGCTGCTTAAACAGT
GGATTGACCGGCCGCTTATCAGAGTCAATCAAATCGAAGAGCGCCAAGAAATGGTGGAAACATTGATGTCCCATTTCTTT
GAACGGGAAGATCTGCGTGAACGTTTAAAAGAAGTATATGACTTAGAACGCCTTGCCGGCCGCGTTGCATTCGGAAATGT
CAATGCCCGGGATTTGATTCAGCTGAAGGAATCGTTAAAGCAAGTTCCTGGCATCAAACAGCTGGTTGCTTCACTGGCTC
ATGACAAGGCCAAGGAACGTGCAAAGCGCATTGACCCTTGCGGGGATGTACTTAAACTGCTGGAAGAAGCGCTGTACGAA
AACCCTCCTTTATCGGTAAAAGAAGGGAACCTGATTAAAGATGGTTATAATCAAAAGCTTGATGAATATCGTGATGCAAG
CAGAAACGGAAAAGACTGGATTGCCCGCTTGGAACAGCAGGAGCGGGAATACACAGGCATTCGCTCTTTAAAGGTCGGCT
TTAATAAAGTTTTCGGTTATTACATTGAAGTGACTAAAGCAAACTTGCATTTGCTTGAGGAAGGGCGTTATGAGCGGAAG
CAGACGTTAACCAATGCAGAGCGCTACATTACACCTGAATTAAAAGAAAAAGAAGCGCTCATTTTAGAGGCGGAAAATAA
CATCTGTGAGCTGGAGTACGAGCTGTTTACCGAGCTGCGCGAGAAAGTGAAGCAGTATATTCCGCGGCTGCAGTTGCTTG
CAAAACAGATGAGCGAGCTGGACGCACTGCAATGCTTTGCGACAATCAGTGAAAATCGCCACTACACGAAACCAGAGTTC
TCTAAAGATGAAGTCGAAGTGATTGAAGGCAGACACCCGGTTGTTGAAAAAGTCATGGACAGCCAGGAATATGTCCCGAA
CAACTGTATGATGGGCGATAACAGACAAATGCTTCTCATTACAGGTCCAAACATGTCAGGGAAAAGCACGTATATGAGAC
AAATCGCGCTCATTTCCATTATGGCGCAAATCGGCTGCTTTGTACCCGCGAAAAAAGCGGTGCTCCCGATTTTCGATCAA
ATTTTTACGCGAATCGGCGCTGCAGATGATTTGATTTCCGGACAAAGTACATTTATGGTAGAAATGCTTGAAGCGAAAAA
TGCGATTGTCAATGCGACGAAAAACAGCCTCATTCTGTTTGATGAAATCGGGCGGGGAACGTCCACTTATGACGGCATGG
CGCTGGCACAGGCGATTATTGAATATGTTCACGATCATATCGGCGCCAAGACGCTGTTCAGCACACACTATCACGAGCTG
ACCGTTCTTGAGGACAAGCTGCCCCAGCTGAAAAACGTTCATGTTCGCGCTGAAGAATATAACGGAACGGTTGTCTTTCT
TCATCAAATTAAAGAAGGTGCCGCTGATAAAAGCTATGGTATCCATGTAGCTCAGCTTGCCGAACTGCCGGGAGATCTGA
TTGCGCGCGCTCAAGATATTTTAAAAGAGCTTGAGCATTCAGGAAACAAACCGGAAGTGCCGGTGCAGAAACCTCAGGTG
AAAGAAGAGCCGGCACAGCTGTCCTTTTTTGACGAAGCGGAAAAGCCGGCTGAAACACCAAAGCTTTCAAAAAAAGAAAA
GCAAGTGATCGATGCTTTCAAATCACTTAATATACTGGATATGACACCGCTTGAAGCGATGAATGAAATGTACAAGCTGC
AAAAGAAATTACATTAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.357	99.65	0.492
mutS	Pseudomonas stutzeri strain ATCC 17587	39.135	100	0.401