Detailed information NTG0293175

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: DK181_RS08630
• Genome accession: NZ_CP029490
• Coordinates: 1776329..1776919 (-)
• Length: 196 a.a.
• NCBI ID: WP_002963348.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain SL1
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1771329..1781919

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK181_RS08605 (DK182_08605)	-	1771885..1772838 (-)	954	WP_002962683.1	branched-chain amino acid ABC transporter permease	-
DK181_RS08610 (DK182_08610)	-	1772842..1773723 (-)	882	WP_002962685.1	branched-chain amino acid ABC transporter permease	-
DK181_RS08615 (DK182_08615)	-	1773773..1774960 (-)	1188	WP_002962687.1	ABC transporter substrate-binding protein	-
DK181_RS08620 (DK182_08620)	-	1775531..1775803 (-)	273	WP_002963346.1	DUF2129 domain-containing protein	-
DK181_RS08625 (DK182_08625)	-	1775815..1776258 (-)	444	WP_002963347.1	YlbF family regulator	-
DK181_RS08630 (DK182_08630)	clpP	1776329..1776919 (-)	591	WP_002963348.1	ATP-dependent Clp protease proteolytic subunit	Regulator
DK181_RS08635 (DK182_08635)	upp	1777463..1778092 (-)	630	WP_002963394.1	uracil phosphoribosyltransferase	-
DK181_RS08640 (DK182_08640)	-	1778496..1779650 (-)	1155	WP_002960338.1	MalY/PatB family protein	-
DK181_RS08645 (DK182_08645)	-	1779743..1780837 (-)	1095	WP_002960340.1	cystathionine gamma-synthase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21519.57 Da
• Isoelectric Point: 4.6260

>NTDB_id=293175 DK181_RS08630 WP_002963348.1 1776329..1776919(-) (clpP) [Streptococcus sobrinus strain SL1]
MIPVVIEQTSRGERSYDIYSRLLKDRIVMLTGPVEDNMANSIIAQLLFLDAQDSTKDIYLYVNSPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPHAEYMIHQPMGGTGAGTQQSDLTIAAEHLLQTRETLEKILADNSGQ
SLKKIHADAERDNWMTAKETLDYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=293175 DK181_RS08630 WP_002963348.1 1776329..1776919(-) (clpP) [Streptococcus sobrinus strain SL1]
ATGATCCCAGTAGTTATTGAACAAACCAGCCGTGGGGAACGCTCCTACGATATTTATTCTCGCCTTTTAAAAGACCGCAT
TGTCATGTTGACAGGTCCAGTTGAGGACAATATGGCTAACTCCATCATTGCCCAACTGCTTTTCTTAGATGCCCAGGATA
GTACTAAGGACATCTACCTCTATGTTAATAGCCCAGGTGGCTCTGTCTCAGCTGGTTTGGCTATTGTTGACACCATGAAT
TTCATCAAGTCAGATGTCCAAACCATTGTTATGGGGATGGCAGCTTCTATGGGGACCATCATCGCTTCCAGCGGTGCCAA
AGGCAAACGCTTTATGCTCCCTCACGCTGAATACATGATTCACCAGCCAATGGGTGGTACTGGTGCCGGTACTCAACAAT
CTGATCTAACTATCGCTGCTGAACATCTCTTGCAAACTCGTGAAACACTTGAAAAAATCTTAGCTGACAATTCAGGTCAA
AGTCTCAAGAAGATTCATGCCGATGCCGAACGTGATAACTGGATGACAGCCAAAGAAACCCTTGATTATGGCTTCATTGA
CGAAATCATGGAAAACAATGAATTGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	88.776	100	0.888
clpP	Streptococcus pneumoniae D39	89.231	99.49	0.888
clpP	Streptococcus pneumoniae Rx1	89.231	99.49	0.888
clpP	Streptococcus pneumoniae R6	89.231	99.49	0.888
clpP	Streptococcus pneumoniae TIGR4	89.231	99.49	0.888
clpP	Streptococcus thermophilus LMD-9	87.755	100	0.878
clpP	Streptococcus thermophilus LMG 18311	87.755	100	0.878
clpP	Streptococcus pyogenes JRS4	86.735	100	0.867
clpP	Streptococcus pyogenes MGAS315	86.735	100	0.867
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	100	0.842
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	100	0.837
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561