Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DF184_RS02230 Genome accession   NZ_CP029398
Coordinates   435037..436329 (+) Length   430 a.a.
NCBI ID   WP_109371177.1    Uniprot ID   -
Organism   Streptococcus suis strain HN105     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 430037..441329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS02205 (DF184_02205) - 430842..431483 (+) 642 WP_002937025.1 response regulator transcription factor -
  DF184_RS02210 (DF184_02210) - 431533..432933 (+) 1401 WP_024377222.1 Cof-type HAD-IIB family hydrolase -
  DF184_RS02215 (DF184_02215) - 432935..433306 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  DF184_RS02220 (DF184_02220) cysK 433332..434258 (-) 927 WP_109371175.1 cysteine synthase A -
  DF184_RS02225 (DF184_02225) - 434348..434980 (-) 633 WP_044769501.1 YigZ family protein -
  DF184_RS02230 (DF184_02230) comFA/cflA 435037..436329 (+) 1293 WP_109371177.1 DEAD/DEAH box helicase Machinery gene
  DF184_RS02235 (DF184_02235) - 436322..436987 (+) 666 WP_105115837.1 ComF family protein -
  DF184_RS02240 (DF184_02240) raiA 437064..437606 (+) 543 WP_014637536.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48958.50 Da        Isoelectric Point: 9.1612

>NTDB_id=292267 DF184_RS02230 WP_109371177.1 435037..436329(+) (comFA/cflA) [Streptococcus suis strain HN105]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKETGVQVFLTATSTDEL
DKKVRTGKLNRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAVAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=292267 DF184_RS02230 WP_109371177.1 435037..436329(+) (comFA/cflA) [Streptococcus suis strain HN105]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCGGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGGCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCAACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCTTAGCCAGTCCTCGAATCGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAACCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAACCGTCTTAGTTTGCCAAGGCGATTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATCGTTGAGGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTAACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCGGGCCGGGTCGGCAGGAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAGTCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGATATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.053

100

0.672
  comFA/cflA Streptococcus pneumoniae Rx1

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae D39

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae R6

66.357

100

0.665
  comFA/cflA Streptococcus pneumoniae TIGR4

66.357

100

0.665
  comFA/cflA Streptococcus mitis SK321

65.893

100

0.66
  comFA Lactococcus lactis subsp. cremoris KW2

54.156

92.326

0.5
  comFA Latilactobacillus sakei subsp. sakei 23K

38.051

100

0.381
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment