Detailed information NTG0291397

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DG474_RS01115
• Genome accession: NZ_CP029257
• Coordinates: 210709..211719 (+)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis strain CCUG 53468
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 205709..216719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG474_RS01090 (DG474_01100)	-	205941..207263 (+)	1323	WP_255778351.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-
DG474_RS01095 (DG474_01105)	folE	207244..207798 (+)	555	WP_000380933.1	GTP cyclohydrolase I FolE	-
DG474_RS01100 (DG474_01110)	folK	208039..208860 (+)	822	WP_255778354.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
DG474_RS01105 (DG474_01115)	-	208853..210136 (+)	1284	WP_255778356.1	DUF308 domain-containing protein	-
DG474_RS01110 (DG474_01120)	-	210187..210504 (-)	318	WP_000886045.1	DUF960 domain-containing protein	-
DG474_RS01115 (DG474_01125)	ccpA	210709..211719 (+)	1011	WP_001090635.1	catabolite control protein A	Regulator
DG474_RS01120 (DG474_01130)	-	211773..212735 (-)	963	WP_061426607.1	asparaginase	-
DG474_RS01125 (DG474_01135)	-	212801..214192 (+)	1392	WP_000453116.1	Cof-type HAD-IIB family hydrolase	-
DG474_RS01130 (DG474_01140)	-	214689..216668 (+)	1980	WP_139689526.1	CAP domain-containing protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=291397 DG474_RS01115 WP_001090635.1 210709..211719(+) (ccpA) [Streptococcus oralis strain CCUG 53468]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=291397 DG474_RS01115 WP_001090635.1 210709..211719(+) (ccpA) [Streptococcus oralis strain CCUG 53468]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCAAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCGAACATTACCAATGGTTATTTCTCA
ACGCTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTAGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTAGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTATCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGTGAGGGATTGGTCTTTGAATCAAAATACAGCTATGATGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTGTTGAATGGTTTGGCTGACCATGGCGTATCTGTGCC
GGAAGAGTTTGAAATCATTACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGATCTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568