Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A1D75_RS24400 Genome accession   NZ_CP034806
Coordinates   4678309..4678941 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2010C-3347     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4673309..4683941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A1D75_RS24375 yheS 4673478..4675391 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  A1D75_RS24380 yheT 4675391..4676413 (+) 1023 WP_000057377.1 hydrolase -
  A1D75_RS24385 yheU 4676407..4676625 (+) 219 WP_000907085.1 YheU family protein -
  A1D75_RS24390 prkB 4676679..4677548 (+) 870 WP_001274677.1 phosphoribulokinase -
  A1D75_RS24395 yhfA 4677603..4678007 (-) 405 WP_001148908.1 OsmC family protein -
  A1D75_RS24400 crp 4678309..4678941 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A1D75_RS24405 yhfK 4678992..4681082 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A1D75_RS24410 argD 4681149..4682369 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A1D75_RS24415 pabA 4682455..4683018 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  A1D75_RS24420 fic 4683050..4683652 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  A1D75_RS24425 yhfG 4683642..4683809 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=291335 A1D75_RS24400 WP_000242755.1 4678309..4678941(+) (crp) [Escherichia coli strain 2010C-3347]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=291335 A1D75_RS24400 WP_000242755.1 4678309..4678941(+) (crp) [Escherichia coli strain 2010C-3347]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467