Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A0I37_RS12410 Genome accession   NZ_CP034799
Coordinates   2606399..2607031 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2009C-4687     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2601399..2612031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0I37_RS12385 yhfG 2601531..2601698 (+) 168 WP_000736862.1 YhfG family protein -
  A0I37_RS12390 fic 2601688..2602290 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  A0I37_RS12395 pabA 2602322..2602885 (+) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  A0I37_RS12400 argD 2602971..2604191 (+) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A0I37_RS12405 yhfK 2604258..2606348 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A0I37_RS12410 crp 2606399..2607031 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A0I37_RS12415 yhfA 2607333..2607737 (+) 405 WP_001148908.1 OsmC family protein -
  A0I37_RS12420 prkB 2607792..2608661 (-) 870 WP_001274677.1 phosphoribulokinase -
  A0I37_RS12425 yheU 2608715..2608933 (-) 219 WP_000907085.1 YheU family protein -
  A0I37_RS12430 yheT 2608927..2609949 (-) 1023 WP_000057377.1 hydrolase -
  A0I37_RS12435 yheS 2609949..2611862 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=291086 A0I37_RS12410 WP_000242755.1 2606399..2607031(-) (crp) [Escherichia coli strain 2009C-4687]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=291086 A0I37_RS12410 WP_000242755.1 2606399..2607031(-) (crp) [Escherichia coli strain 2009C-4687]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467