Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   SGO_RS09385 Genome accession   NC_009785
Coordinates   1987962..1988915 (-) Length   317 a.a.
NCBI ID   WP_012130935.1    Uniprot ID   A8AZH3
Organism   Streptococcus gordonii str. Challis substr. CH1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1982962..1993915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGO_RS09365 (SGO_1913) - 1983630..1984961 (-) 1332 WP_041789910.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  SGO_RS09370 (SGO_1914) folP 1984966..1985931 (-) 966 WP_012130932.1 dihydropteroate synthase -
  SGO_RS09375 (SGO_1915) - 1986009..1986674 (-) 666 WP_012130933.1 CPBP family intramembrane glutamic endopeptidase -
  SGO_RS09380 (SGO_1916) - 1986722..1987912 (-) 1191 WP_012130934.1 acetate kinase -
  SGO_RS09385 (SGO_1917) comYH 1987962..1988915 (-) 954 WP_012130935.1 class I SAM-dependent methyltransferase Machinery gene
  SGO_RS09390 (SGO_1918) comGG 1988946..1989377 (-) 432 WP_223341947.1 competence type IV pilus minor pilin ComGG -
  SGO_RS09395 (SGO_1919) comGF/cglF 1989358..1989795 (-) 438 WP_012130937.1 competence type IV pilus minor pilin ComGF Machinery gene
  SGO_RS09400 (SGO_1920) comGE/cglE 1989779..1990072 (-) 294 WP_012130938.1 competence type IV pilus minor pilin ComGE Machinery gene
  SGO_RS09405 (SGO_1921) comYD 1990044..1990472 (-) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  SGO_RS09410 (SGO_1922) comYC 1990432..1990749 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  SGO_RS09415 (SGO_1923) comYB 1990746..1991780 (-) 1035 WP_012130941.1 competence type IV pilus assembly protein ComGB Machinery gene
  SGO_RS09420 (SGO_1924) comYA 1991692..1992651 (-) 960 WP_012130942.1 competence type IV pilus ATPase ComGA Machinery gene
  SGO_RS09425 (SGO_1925) - 1992753..1993121 (-) 369 WP_012130943.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36000.10 Da        Isoelectric Point: 4.8695

>NTDB_id=29101 SGO_RS09385 WP_012130935.1 1987962..1988915(-) (comYH) [Streptococcus gordonii str. Challis substr. CH1]
MNFEKIEEAYTLLLENVQVIQNKLSTNFYDALIEQNGIYLDGQTDLEIVKKNHQTLKSLKLSREEWRRAYQFILMKAAQT
EPLQANHQFTPDAIGFLLIFIIDQLMVASDITLLEMGSGTGNLAETILNNSQKEIDYLGLEIDDLLIDLSASIAEVMGSK
AHFAQGDAVRPQVLKESDLIISDLPVGYYPDDQIASRYQVASQTEHTYAHHLLMEQALKYLKADGYAIFLAPNHLLTSPQ
SDLLKSWLKDNASLVAMIALPEKLFASVSQAKTVFVLQKQKNIKTEPFAYALTDLQNHDEITRFRESFQKWRKVSEN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=29101 SGO_RS09385 WP_012130935.1 1987962..1988915(-) (comYH) [Streptococcus gordonii str. Challis substr. CH1]
ATGAATTTTGAAAAAATCGAAGAAGCCTATACGCTCCTTTTAGAAAATGTCCAAGTCATTCAAAACAAGCTTTCAACTAA
TTTTTATGATGCCTTAATCGAGCAAAACGGTATCTATTTGGATGGACAAACGGACTTAGAAATCGTTAAAAAGAATCATC
AGACCTTGAAGAGCTTAAAGCTAAGCAGAGAAGAATGGCGCAGAGCCTATCAGTTCATTCTGATGAAGGCTGCTCAGACA
GAGCCTTTGCAAGCCAATCATCAGTTTACACCAGATGCCATTGGTTTTCTGCTGATTTTCATCATCGACCAGCTGATGGT
AGCATCAGATATTACTCTTCTTGAGATGGGGAGCGGAACCGGAAATCTTGCAGAGACAATCCTGAACAATAGTCAGAAAG
AGATTGATTATCTAGGATTAGAGATTGATGATTTACTGATTGACCTATCTGCCAGTATTGCAGAAGTGATGGGTTCAAAG
GCACATTTTGCCCAGGGAGATGCTGTGCGCCCTCAAGTTCTAAAAGAGAGCGACTTGATTATTAGTGATCTGCCTGTCGG
TTACTATCCGGATGATCAGATTGCCAGTCGCTACCAGGTAGCCAGTCAGACGGAGCACACCTATGCTCATCATCTATTGA
TGGAGCAGGCTTTAAAGTATTTGAAGGCCGATGGCTATGCAATCTTCTTAGCTCCTAATCACCTCTTAACCAGCCCGCAG
AGCGACTTACTTAAATCCTGGCTCAAAGACAATGCCAGCTTGGTTGCGATGATTGCTTTGCCAGAAAAACTCTTTGCATC
AGTTTCTCAGGCTAAGACGGTTTTTGTTTTGCAAAAACAAAAAAATATAAAAACGGAACCTTTTGCCTATGCATTGACAG
ATCTACAAAATCATGATGAAATTACTCGCTTTCGCGAAAGTTTTCAAAAATGGCGCAAAGTTAGTGAAAACTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.786

98.738

0.58
  comYH Streptococcus mutans UA140

58.786

98.738

0.58

Multiple sequence alignment