Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AYP37_RS13380 Genome accession   NZ_CP034797
Coordinates   2444133..2444765 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 08-3918     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2439133..2449765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AYP37_RS13355 yheS 2439302..2441215 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  AYP37_RS13360 yheT 2441215..2442237 (+) 1023 WP_000057377.1 hydrolase -
  AYP37_RS13365 yheU 2442231..2442449 (+) 219 WP_000907085.1 YheU family protein -
  AYP37_RS13370 prkB 2442503..2443372 (+) 870 WP_001274677.1 phosphoribulokinase -
  AYP37_RS13375 yhfA 2443427..2443831 (-) 405 WP_001148908.1 OsmC family protein -
  AYP37_RS13380 crp 2444133..2444765 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AYP37_RS13385 yhfK 2444816..2446906 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AYP37_RS13390 argD 2446973..2448193 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AYP37_RS13395 pabA 2448279..2448842 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  AYP37_RS13400 fic 2448874..2449476 (-) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  AYP37_RS13405 yhfG 2449466..2449633 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290996 AYP37_RS13380 WP_000242755.1 2444133..2444765(+) (crp) [Escherichia coli strain 08-3918]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290996 AYP37_RS13380 WP_000242755.1 2444133..2444765(+) (crp) [Escherichia coli strain 08-3918]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467