Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   A1D74_RS20575 Genome accession   NZ_CP034794
Coordinates   3944274..3944906 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 06-3462     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3939274..3949906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A1D74_RS20550 yheS 3939443..3941356 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  A1D74_RS20555 yheT 3941356..3942378 (+) 1023 WP_000057377.1 hydrolase -
  A1D74_RS20560 yheU 3942372..3942590 (+) 219 WP_000907085.1 YheU family protein -
  A1D74_RS20565 prkB 3942644..3943513 (+) 870 WP_001274677.1 phosphoribulokinase -
  A1D74_RS20570 yhfA 3943568..3943972 (-) 405 WP_001148908.1 OsmC family protein -
  A1D74_RS20575 crp 3944274..3944906 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  A1D74_RS20580 yhfK 3944957..3947047 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  A1D74_RS20585 argD 3947114..3948334 (-) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  A1D74_RS20590 pabA 3948420..3948983 (-) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  A1D74_RS20595 fic 3949015..3949617 (-) 603 WP_001280652.1 putative adenosine monophosphate-protein transferase Fic -
  A1D74_RS20600 yhfG 3949607..3949774 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290932 A1D74_RS20575 WP_000242755.1 3944274..3944906(+) (crp) [Escherichia coli strain 06-3462]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290932 A1D74_RS20575 WP_000242755.1 3944274..3944906(+) (crp) [Escherichia coli strain 06-3462]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467