Detailed information NTG0290925

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: DD562_RS08970
• Genome accession: NZ_CP029172
• Coordinates: 1769344..1771545 (-)
• Length: 733 a.a.
• NCBI ID: WP_001807826.1
• Uniprot ID: A0AAP7YX23
• Organism: Staphylococcus aureus strain PTDrAP2
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1764344..1776545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DD562_RS08955 (DD562_08955)	lepA	1765848..1767671 (-)	1824	WP_000368338.1	translation elongation factor 4	-
DD562_RS08960 (DD562_08960)	rpsT	1768017..1768268 (+)	252	WP_001274017.1	30S ribosomal protein S20	-
DD562_RS08965 (DD562_08965)	holA	1768313..1769287 (-)	975	WP_001282570.1	DNA polymerase III subunit delta	-
DD562_RS08970 (DD562_08970)	comEC	1769344..1771545 (-)	2202	WP_001807826.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DD562_RS08975 (DD562_08975)	-	1771550..1772011 (-)	462	WP_000439690.1	ComE operon protein 2	-
DD562_RS08980 (DD562_08980)	comEA	1772103..1772726 (-)	624	WP_234418051.1	ComEA family DNA-binding protein	Machinery gene
DD562_RS08985 (DD562_08985)	-	1772829..1773545 (-)	717	WP_000084838.1	class I SAM-dependent DNA methyltransferase	-
DD562_RS08990 (DD562_08990)	rsfS	1773548..1773901 (-)	354	WP_001088020.1	ribosome silencing factor	-
DD562_RS08995 (DD562_08995)	yqeK	1773902..1774486 (-)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
DD562_RS09000 (DD562_09000)	nadD	1774476..1775045 (-)	570	WP_000725164.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
DD562_RS09005 (DD562_09005)	yhbY	1775048..1775338 (-)	291	WP_000955234.1	ribosome assembly RNA-binding protein YhbY	-
DD562_RS09010 (DD562_09010)	aroE	1775342..1776148 (-)	807	WP_000666746.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84968.25 Da
• Isoelectric Point: 10.0424

>NTDB_id=290925 DD562_RS08970 WP_001807826.1 1769344..1771545(-) (comEC) [Staphylococcus aureus strain PTDrAP2]
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNPQFNERVQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVIDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFVFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGLLSNLIFVPYYSIILFPLSILFFITSHFIVGLMPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVINDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGELEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNVKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSNSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=290925 DD562_RS08970 WP_001807826.1 1769344..1771545(-) (comEC) [Staphylococcus aureus strain PTDrAP2]
TTGCTGTATGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTGCTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCTCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATCCTCAGTTTAATGAGCGTGTTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTATTGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGTCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGAATTATGGCATTGATTACTGGTGA
CGTAAAAGAAATTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGGTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTCTTAATTTATCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCAAGTGCTGTAAGAGCTATAATAATGACAACGCTTGT
ACTGCTTATTACTAAGCAAATTAAAATAAAGGGTATTCAGCTATTAGCATTTGTATTTATAATTATGTTTATTTTGAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAACTT
TCATCAACTTCAATGGGTGGGATTATTATCTAATTTGATTTTTGTACCATACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAATGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAAT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGTGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTAATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAATTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTATAACGTTAAACTTATGGATGTAAGGCAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAATATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTTCTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGAAAGAACAATATGTATCATCTTCCTAACATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGCCAACAAAACGGTCAAGTTACAATAGACTTAGATGATAATTTA
AAAGTTGATTCAAACTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (183-441)

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.226	100	0.982
comEC	Staphylococcus aureus MW2	97.817	100	0.978