Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DR788_RS25600 Genome accession   NZ_CP034792
Coordinates   5052392..5053024 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2009C-3378     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5047392..5058024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DR788_RS25575 yhfG 5047524..5047691 (+) 168 WP_000736862.1 YhfG family protein -
  DR788_RS25580 fic 5047681..5048283 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  DR788_RS25585 pabA 5048315..5048878 (+) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  DR788_RS25590 argD 5048964..5050184 (+) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  DR788_RS25595 yhfK 5050251..5052341 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  DR788_RS25600 crp 5052392..5053024 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  DR788_RS25605 yhfA 5053326..5053730 (+) 405 WP_001148908.1 OsmC family protein -
  DR788_RS25610 prkB 5053785..5054654 (-) 870 WP_001274677.1 phosphoribulokinase -
  DR788_RS25615 yheU 5054708..5054926 (-) 219 WP_000907085.1 YheU family protein -
  DR788_RS25620 yheT 5054920..5055942 (-) 1023 WP_000057377.1 hydrolase -
  DR788_RS25625 yheS 5055942..5057855 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=290878 DR788_RS25600 WP_000242755.1 5052392..5053024(-) (crp) [Escherichia coli strain 2009C-3378]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=290878 DR788_RS25600 WP_000242755.1 5052392..5053024(-) (crp) [Escherichia coli strain 2009C-3378]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment