Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CRG85_RS09625 Genome accession   NZ_CP034787
Coordinates   1971885..1972541 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ECCNB20-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1966885..1977541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRG85_RS09595 (CRG85_09595) dcyD 1967765..1968751 (+) 987 WP_104769284.1 D-cysteine desulfhydrase -
  CRG85_RS09600 (CRG85_09600) tcyL 1968766..1969434 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CRG85_RS09605 (CRG85_09605) tcyN 1969431..1970183 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CRG85_RS09610 (CRG85_09610) sdiA 1970412..1971134 (+) 723 WP_032256217.1 transcriptional regulator SdiA -
  CRG85_RS09615 (CRG85_09615) yecF 1971202..1971426 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CRG85_RS09620 (CRG85_09620) yecU 1971413..1971589 (-) 177 WP_001696741.1 protein YecU -
  CRG85_RS27065 - 1971672..1971743 (-) 72 Protein_1858 transcriptional regulator -
  CRG85_RS09625 (CRG85_09625) letA 1971885..1972541 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CRG85_RS09630 (CRG85_09630) uvrC 1972538..1974370 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  CRG85_RS09635 (CRG85_09635) pgsA 1974427..1974975 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CRG85_RS09655 (CRG85_09655) yecA 1975624..1976289 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=290761 CRG85_RS09625 WP_000611335.1 1971885..1972541(+) (letA) [Escherichia coli strain ECCNB20-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=290761 CRG85_RS09625 WP_000611335.1 1971885..1972541(+) (letA) [Escherichia coli strain ECCNB20-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAAGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486